Intro to Motor Systems Flashcards
Motor Systems Concepts
Somatic Motor System (GSE)
- movements intitiated (or modulated by) voluntary intent
- targets = striated mm
- reflex component
Visceral Motor System (GVE)
- part of autonomic nervous system
- targets = smooth/cardiac m, glands
Motor Systems Concepts
Motivation (frontal lobe)
- ideation of motor plan
- input from
- sensory stimuli (parietal motor area)
- emotions/memory (limbic syste)
Motor Plan (premotor cx)
- blueprint or module for movement
- premotor cx (lateral BA6 & 8)
Motor Systems Concepts
Action (primary motor cx)
- UMN systems
- locations:
- primary motor cx
- brainstem nuclei
- UMN fibers influence motor neurons in spinal cord (& cranial n motor nuclei) = LMN
- All systems converge on LMNs to provide movement
Alpha LMNs
Synapse on skeletal muscle
Final common pathway
Always excitatory - release NT=contraction
Target ipsilateral to soma
Large
Alpha LMNs continued
Found in
- sp cord ventral horn & cranial nerve motor nuclei
Have baseline activity, changed by excitatory & inhibitory inputs
Motor Units
Motor Unit = 1 LMN + all m fibers it innervates
Size related to function (fine control vs power)
- small number for fine control
1 LMN innervates many fibers
Each m fiber has motor units of various sizes (although certain sizes may predominate)
Motor Units Continued
AP in motor axon is “all or nothing”
Regulate strength of muscle contraction via
- AP frequency
- Recruitment (#motor units firing proportional to strength)
- ordered by size (smaller motor units recruited first, then larger)
- “Size Principle”
Upper Motor Neurons
Axons from brain, influence LMN
- Directly (few) or indirectly (most)
- Excitatory or inhibitory
Never synapse on muscle
Cerebral cx & brainstem
UMN
8 different UMN pathways drive LMNs in spinal cord
- 2 from primary motor cx
- rest from brainstem nuclei
Lateral Motor System
- Distal limb mm
- precise, fractionated movements
Medial Motor Systems
- Axial/Proximal limb mm
- Postural movements
Intro to Cortical UMN Systems
Two Cortical UMN Pathways:
- Corticospinal Tract (Lateral
- Corticobulbular Tract
Important features of LCST:
- large motor tract of humans
- contralateral projections
- some UMNs synapse directly on LMNs
- critical for complex, fractionated movements
Anatomy of the LCST
Premotor Cx - lateral BA6 &8
Motor planning
- most active at start of voluntary movement
Supplementary Motor Cx - medial BA6 & 8
Motor planning
- interconnected w/contralateral side = bimanual movements
Corticobulbar Tract
Corticobulbar similar to corticspinal, except:
- Terminate in brainstem
- Influences
- cranial nerve motor nuclei (LMNs)
- AND UMN nuclei
Corticobulbar fibers ALSO:
Influence activity in brainstem UMN nuclei
- vestibular nuclei
- reticular nuclei
- red nucleus
These nuclei give rise to medial motor systems (control of axial/proximal limb mm) - gain voluntary control of these by sending info from cx to these nuclei via corticobulbar tract
LMN Damage
- LMN damage produce LMN signs
- Hypo- to Areflexia (continuum)
- hypo- to Atonia - decrease stretch reflex
- Paralysis/paresis
- loss of trophic relationships w/motor neuron
- neurogenic atrophy
- EMG changes: spontaneous activity in mm
- fasciculations and fibrilations
UMN Damage
Produces UMN Signs
- Normal to Hyperreflexia
- Increase stretch reflex - hypertonia
- Appearance of pathological reflexes
- Paresis/paralysis
- spastic (especially in antigravity mm)
- Disuse atrophy
- Few EMG changes