Intro to Microbiology Flashcards

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1
Q

What is the fundamental difference between eukaryotes and prokaryotes?

A

Prokaryote nuclei are not membrane bound. Eukaryote nuclei are membrane bound
(Prokaryotes are more primitive than eukaryotes and therefore haven’t develop membrane for nucleus)

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2
Q

Which bacterium is responsible for tooth decay?

A

Streptococcus mutants (gram negative coco that produces slime helping it stick to teeth)

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3
Q

What is the viral nucleic acid cord comprised of?

A

Either DNA or RNA (but not both)

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4
Q

How are retroviruses unusual? (in terms of their viral genome)

A

Retroviruses are unusual because they have an RNA copy of the genome but upon infection of a host cell a cDNA copy of the virus genome s made using the enzyme reverse transcriptase

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5
Q

What are prions?

A

Protein particle that can be infectious

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6
Q

True or false: fungi are prokaryotes?

A

False. Fungi are eurokayotes

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7
Q

What are the names of these different shaped bacteria:

  • round shaped
  • rod shaped
  • spiral shaped
A
  • round shaped =cocci
  • rod shaped =bacillus
  • spiral shaped =spirilium
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8
Q

What is the vector for malaria?

A

Female anopheles mosquito

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9
Q

Give some examples of protozoan infections

A
  • Malacia
  • Toxoplasmosis
  • Amoebic meningitis/dysentery
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10
Q

Which sites in the body are considered sterile?

A
  • Lower respiratory tract
  • Upper genital tract
  • Urinary tract
  • Pleural cavity
  • Spinal cord and meninges
  • Middle ear
  • Peritoneal cavity
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11
Q

Where do coagulase-negative staphylococci, staph aura and p.acnes colonise?

A

*Skin and orifices

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12
Q

Where is the main carrier site for staph aureus?

A

The nose

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13
Q

Where do strep pyogenes(a), haemophilia influenza, strep pneumonia and neisseria meningitidis live?

A

The pharynx

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14
Q

What is the role of lactobacillus acidophilus in the vagina and when does it colonise females?

A

It ferments glycogen to maintain low pH, in the vagina preventing colonisation by other species. Colonises after puberty due to circulating oestrogen which induce glycogen production

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15
Q

The vast majority of bacteria in the stomach and small intestine are:

a) aerobic
b) anaerobic
c) trick question there are no bacteria in the stomach

A

A. Aerobic e.g. lactobacilli and h.pylori

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16
Q

The vast majority of bacteria in the large intestine are:

a) aerobic
b) anaerobic
c) trick question

A

B. Anerobic

17
Q

Which bacteria live in the stomach and small intestine?

A

Lactobacilli and h.pyloria

18
Q

Which bacteria live in the large intestine?

A

Faculative aerobic:

  • E. coli
  • Klebseilla
  • Enterobacter

Anaerobe full time:
-Clostridium
Bifidobateria
Bacteroides

19
Q

What are the benefits of normal flora?

A
  • Induce cross-reactive antibodies
  • resist colonistion -manipulate pH and act as antibacterial agents
  • synthesise and excrete vitamins -K and B12
20
Q

Diarrhoea and pseudomembranous colitis are symptoms of an overgrowth of which bacteria?

A

C. difficile

21
Q

which bacterium in the colon secretes vitamin K?

A

E.coli

22
Q

What are endotoxins?

A

Components of gram negative bacterial cell wall:

  • E.coli
  • Neisseria meningitides released from damaged / dead cells
23
Q

What is the cause of systemic inflammatory response syndrome? (SIRS)

A

LPS endotoxin causing and exaggerated immune response

24
Q

What is out of control in systemic inflammatory response syndrome?

A
  • T cell response
  • clotting cascade
  • uncontrolle activation of complement