Intro to Endo

Question 1

formation of hormone-receptor complex depends on

Answer 1

rate of hormone secretion
protein binding
metabolism of hormone

Question 2

on conc/response curve, a shift down is a

Answer 2

decrease in responsiveness and it may be due to a decreased number of target cells

Question 3

on conc/response curve, a shift to the right is

Answer 3

a decrease in sensitivity and may be due to medication antagonist

Question 4

permissiveness

Answer 4

hormone A does not produce a significant change in biological response
hormone B does produce a significant change in biological response

Question 5

counter-regulation

Answer 5

two hormones regulate the same variable, one hormone increases the varibale and the other hormoen decreases the variable

insulin and glucagon

Question 6

trophic hormone

Answer 6

hormones that stimualte the secretion of another hormone from an endocrine gland
hromones required for growth and maintainence of target cells

Question 7

synergy

Answer 7

hormones A and B both produce a significant change in the same biological response, but together they produce a response much greater than the sum

Question 8

peptide hormones

Answer 8

storage of pre-formed hormone allows for rapid response
- hydrophilic -
do NOT reqiure transport protein

Question 9

peptide hormone receptors on cell surface

Answer 9

ion channel
protein kinase
cytoplasmic JAK
G-protein linked receptors

Question 10

steroid hormone

Answer 10

synthesized from cholesterol and upon demand
slow response to stimulus
DO REQUIRE transport protein

Question 11

hypothalamic neurocrine hormones

Answer 11

GnRH
GHRH
SS
TRH
DA
CRH