Intro To Cellular Anatomy Flashcards
Unifying themes of bio
- Cell theory:
1) basic unit of life
2) all living thing made of cells
3) cells arise from other cells - Molecular basis of inheritance: continuity of life (faithful copying and transmission of DNA for proper functioning of cell)
- Relationship b/w structure & function
- Evolutionary change (diversity of life) vs Evolutionary conservation (common elements of living systems)
- Living systems in equilibrium
1) open & far from thermodynamic equilibrium
2) Enzymes catalyze cellular rxn
3) behaviour of individuals unpredictable from nature of units - Info found in DNA dictate cell type & activity (cell receptors dictate gene expression)
Cellular Anatomy
- Cytoplasmic membrane (structure of cell, cell transport, signalling)
- Nucleus
1) Nucleus (chromatin, loosely packed DNA, carries genetic info in cell)
2) Nucleolus (darker region of nucleus, genes for transcription of rRNA & production of ribosomes)
3) Nuclear membrane (envelops, contains nuclear matter)
4) Nuclear pore (pores in membrane, allow passage of material b/w cytoplasm & nucleus) - Ribosomes (protein factories of cell)
1) made of protein & rRNA
2) use code from mRNA & tRNA (synthesize proteins)
3) free or membrane bound
Rough endoplasmic reticulum
1) surface = ribosomes
2) site of protein synthesis (transport from cell, localization to vacuoles, or embedding in plasma membrane)
3) Glycosylation (protein + carb = modified)
Smooth endoplasmic reticulum
1) no ribosomes
2) carb, steroid hormone, lipid synthesis
3) controls intracellular Ca2+ levels
4) detoxification
Golgi Complex
1) individual sacs of cisternae
2) collection, packaging, sorting, & distribution of molecules
3) molecules cis to trans face of golgi complex (to exterior of cell)
Lysosomes
1) arise from golgi complex
2) digestive enzymes = degrade proteins, lipids, carbs
3) defence against pathogens, breakdown of old organelles & cellular waste
Endomembrane System
1) compartmentalize cell
2) molecular transport
3) surface for molecular synthesis
Microbodies
1) membrane bound vesicles w/ enzymes
2) ex: peroxisomes (oxidative enzymes = produce hydrogen peroxide, breakdown of long chain fatty acids)
Vacuoles (plants -central vacuole - & animals)
Membrane: Tonoplast
Channels for water exchange (controls tonicity, intercellular ion concentration, of cell); Water storage & equilibrium
Store & segregate toxins & waste from rest of cell
Mitochondria (both plants & animals)
Metabolizes sugar (produce ATP)
Bacteria size, own DNA, own ribosomes (metabolic specific genes)
Chloroplasts (only in plants)
Energy from sunlight (create sugar & ATP)
Own DNA & ribosomes
Endosymbiotic theory
1) prokaryotic cells first
2) aerobic bacteria: cells compartmentalize, become eukaryotic cells
3) Mitochondria came first (in plants & animals) from bacteria
4) Animals, fungi, certain protists: stay with mitochondria only
4) Plants & certain protists: photosynthetic bacteria adds & becomes chloroplasts