Intro To Cell II Flashcards
Peripheral membrane proteins are attached to the cytoplasmic regions of the lipid bilayer via _____ interactions
Peripheral membrane proteins are attached to the cytoplasmic regions of the lipid bilayer via NON-COVALENT interactions
There are more integral membrane proteins on the ____ face of the cell
Why?
There are more integral membrane proteins on the PROTOPLASMIC face of the cell
Why?
Because proteins associated with the P-face are stabilized by attachment to cytoskeleton
Hereditary spherocytosis occur when _____ is mutated in ______.
_____ are _____ proteins that associate with several membrane proteins to ___________
Hereditary spherocytosis occur when SPECTRIN is mutated in RBCs.
SPECTRINS are CYTOSKELETAL proteins that associate with several membrane proteins to STABILIZE THE BICONCAVE SHAPE OF NORMAL RBCs
Microvilli are made up of the cytoskeleton protein ____ and topped with a _______ (which contains enzymes involved in ______), which terminates in a ____________
Microvilli are made up of the cytoskeleton protein ACTIN and topped with a GLYCOCALYX (which contains enzymes involved in PROTEIN AND CARBOHYDRATE DIGESTION) which terminates in a TERMINAL WEB
Glycocalyx consists of glyco_____, glyco_____, and ______
Glycocalyx consists of glycoPROTEINS, glycoLIPIDS, and PROTEOGLYCANS
The terminal web at mirovillus base contains _______ and _________
The terminal web at mirovillus base contains INTERMEDIATE FILAMENTS and ACTIN
Junctional complex is on the _____ surface of epithelial cells and is made up of _______, ________, _______, ______
Junctional complex is on the LATERAL surface of epithelial cells and is made up of ZONULA OCCLUDENS, ZONULA ADHERENS, MACULA ADHERENS, GAP JCTS
Tubulin is a ______ that contribute to _____, ______, _____, and ______ _______
Tubulin is a DIMER that contributes to CYTOSKELETON, CENTRIOLES, CILIA, and MITOTIC SPINDLES
Enzymes in the smooth ER function in ____ and _____ biosynthesis, _______, and storage for ____ ions.
Enzymes in the smooth ER function in LIPID and STEROID biosynthesis, DETOXIFICATION, and storage for Ca2+ ions.
The outer membrane of the nuclear envelope is contiuous with the _______. _______ can be found on the outer nuclear membrane.
The ________ space is continuous with the RER.
The outer membrane of the nuclear envelope is contiuous with the RER. RIBOSOMES can be found on the outer nuclear membrane.
The PERINUCLEAR space is continuous with the RER.
RER synthesizes proteins that are destined for _____, ____, and the _____.
RER synthesizes proteins that are destined for SECRETION, LYSOSOME, and the MEMBRANE.
In early endosome, _____ and _____ are separated, and the ______ are often recycled to the _______.
In early endosome, RECEPTORS and LIGANDS are separated, and the RECEPTORS are often recycled to the SURFACE.
Proteins assembled on the _____ membrane of the mitochondria _______________ and ___________.
Proteins assembled on the INNER membrane of the mitochondria COUPLE OXIDATION TO PHOSPHORYLATION and ATP SYNTHESIS.
Mitochondrial DNA encodes _______ _______ of the enzymes involved in ______ ______.
However, most mitochondrial proteins are _____________ and enter from the ______ pathway, not the _______ pathway.
Mitochondrial DNA encodes THE HYDROPHOBIC SUBUNITS of the enzymes involved in OXIDATIVE PHOSPHORYLATION.
However, most mitochondrial proteins are ENCODED BY NUCLEAR DNA and enter from the CYTOSOL pathway, not the RER AND GOLGI pathway.
Lysosomes have a _______ which maintains the pH.
Can visualize lysosomes using the dye _____ ____.
Lysosomes have a ATP-DRIVEN PROTON PUMP which maintains the pH.
Can visualize lysosomes using the dye TRYPAN BLUE.
