intro to cardiovascular system Flashcards

1
Q

what do we need the CVS for

A

1) Transport for respiratory gases and nutrients.
2) temperature regulation
3) as a signalling system for distributing hormones, information molecules etc to target tissues
4) male hydraulic device

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2
Q

what is t proportional to

A

x2 (distance squared)

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3
Q

what does the CVS use a combination of

A

convection and diffusion

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4
Q

what is convection

A

movement by pressure gradient

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5
Q

how does the heart create this convection current

A

by creating a pressure difference between arteries and veins

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6
Q

heart cycle

A

1) superior and inferior vena cave deposits deoxygenated blood into the right atrium
2) blood then goes into the right ventricle
3) blood is then pushed out of the right ventricle via the pulmonary artery into the lungs (under lower pressure to allow good gaseous exchange)
4) - blood gets oxygenated by diffusion -
5) it then comes back to the heart and enters into the left atrium via the pulmonary vein
6) blood is then pumped to left ventricle
7) finally pumped out of left ventricle to the rest of the body under high pressure via the aorta.

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7
Q

what do the opening and closing of the valves depend on

A

pressure gradients

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8
Q

systole =

A

contractions (ventricles being emptied of blood)

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9
Q

diastole =

A

relaxations (ventricles being filled with blood)

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10
Q

What is Cardiac output

A

volume of blood ejected from the ventricles per minute

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11
Q

cardiac output equation =

A

SV X HR

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12
Q

what organ’s oxygen supply is relatively in line with how much they need? (they’re output) (3)

A
  • liver
  • GI
  • muscles
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13
Q

what organ is well perfused

A

Kidney

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14
Q

what organs are underperfused (2)

A
  • myocardium
  • brain
    (becomes an issue when there is a clinical problem such as angina e.g. angina / myocardium
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15
Q

CO at rest =

A

70bpm + 70ml = 5litres/min

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16
Q

CO after exercise =

A

180bpm + 120ml = 20 litres/min

17
Q

what are the three main factors controlling cardiac output

A

1) filling pressure - starling’s law
2) sympathetic/parasympathetic nerves
3) chemical factors

18
Q

what do sympathetic nerves release and what receptors do they act on (causes increase in heart rate and contractility so CO increases)

A

NA acting at beta-1-adrenoceptors

19
Q

what do parasympathetic nerves release and what receptors do they act on (decrease in heart electrical activity at the SAN reducing HR)

A

Ach acting at M2 receptors

20
Q

what is blood flow proportional to

A

pressure across blood vessels - greater pressure means greater flow

21
Q

what is blood flow is inversely proportional to

A

resistance - greater resistance means less flow

22
Q

what is darcey’s law

A

Blood flow = (pa - pv) / resistance

23
Q

systemic circulation =

A

high pressure system

24
Q

pulmonary circulation =

A

low pressure system

25
Q

how do arterioles control arterial BP

A

by determining total peripheral resistance which changes blood flow

26
Q

what is parallel circulation

A

when cardiac output is split up to supply individual areas with blood. - getting first hand oxygenate blood

27
Q

what is series ‘portal’ circulation

A

where same blood supply is used between organs e.g. liver receives second hand blood from intestines (contains various nutrients and chemicals from intestines that have been digested)

28
Q

what are the 4 main functional groups of blood vessels

A
  • elastic vessels
  • resistance vessels
  • exchange vessels
  • capacitance vessels