Intro To Biomaterials Flashcards

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1
Q

What is a biomaterial?

A

A material used to be incorporated into the body for repairing, replacing, or assisting damaged, diseased, or missing tissues.

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2
Q

What fields does biomaterials science bridge?

A

Biology and material science, requiring a multidisciplinary approach.

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3
Q

Name one example of a common biomaterial used in skeletal repair.

A

Titanium plates and screws, often used for skull or bone repairs.

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4
Q

What are common materials used in hip replacements?

A

Metal alloys, such as titanium, and plastic liners.

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5
Q

How is synthetic bone created?

A

Using materials like hydroxyapatite, which mimics the structure of natural bone.

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6
Q

What is one major challenge when placing biomaterials in the body?

A

Preventing infection, particularly biofilm formation on the biomaterial surfaces.

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7
Q

What is a biofilm, and why is it problematic?

A

A biofilm is a community of microorganisms that attach to surfaces and resist immune responses and antibiotics.

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8
Q

Name one method used to make biomaterials resistant to microorganisms.

A

Surface modifications, such as adding antimicrobial agents or creating textures to prevent bacterial attachment.

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9
Q

How can light be used in biomaterials research?

A

Certain wavelengths can disinfect wounds, useful in non-sterile environments like battlefields.

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10
Q

What biomaterials are used to treat blocked arteries?

A

Stents (metal) and bypass grafts (often made from polymers like Dacron).

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11
Q

What is a pacemaker classified as, and why?

A

A biomaterial, because it is an inert device implanted in the body to regulate heart function.

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12
Q

What advancements are seen in the third-generation biomaterials?

A

Incorporation of capillaries, embedded cells, and advanced structures for enhanced functionality.

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13
Q

How is 3D printing revolutionizing biomaterials?

A

It enables personalized medicine by creating tailored implants and devices.

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14
Q

How do biomaterials contribute to tissue repair?

A

By providing support or scaffolding for tissue regeneration and replacing damaged tissues.

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15
Q

Why is an interdisciplinary approach important in biomaterials science?

A

It combines knowledge from engineering, biology, and material science to solve complex medical problems.

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16
Q

What is one innovative use of biomaterials in the skeletal system?

A

3D-printed scaffolds for bone repair that mimic natural bone structures.

17
Q

How are biomaterials used in the cardiovascular system?

A

In applications like bypass grafts, stents to open arteries, and mechanical heart valves.

18
Q

What are antibiotic beads used for in surgeries?

A

To combat infections by releasing antibiotics directly at the site of a biomaterial implant.

19
Q

What material is commonly used in bone graft substitutes?

A

Hydroxyapatite, which has a similar composition to bone mineral.

20
Q

What are the benefits of using titanium in implants?

A

High strength, biocompatibility, and resistance to corrosion in the body.

21
Q

How do researchers combat biofilm formation on biomaterials?

A

By designing antimicrobial surfaces, such as textured patterns or coatings that repel bacteria.

22
Q

What advancements are being made in personalized biomaterials?

A

3D printing customized implants tailored to individual anatomical needs.

23
Q

Why are biofilms a significant issue in biomaterials?

A

They protect bacteria from antibiotics and immune responses, leading to persistent infections.

24
Q

What is one physical modification to biomaterials to deter biofilms?

A

Incorporating micro-needle-like textures that puncture bacterial membranes.

25
Q

What is the purpose of cement in joint replacements?

A

To secure implants like knee or hip replacements and ensure stability.

26
Q

What is a common biomaterial used in pacemakers?

A

Biocompatible metals or polymers that are inert and resistant to bodily reactions.

27
Q

What is an example of next-generation biomaterials?

A

Materials that integrate artificial capillaries and embedded cells for enhanced healing.

28
Q

How are biomaterials contributing to regenerative medicine?

A

By developing scaffolds and systems that promote tissue regeneration and functionality.