Intro Lectures Flashcards

1
Q

What is pharmacology

A

The study of interactions of drugs with living systems

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2
Q

What is clinical pharmacology

A

The application of pharmacology principles to patients

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3
Q

What is pharmacy

A

The science of the preparation of drugs

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4
Q

What is toxicology

A

The study of poisons and their treatments

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5
Q

Comparative pharmacology

A

Study of drugs in different species

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6
Q

Veterinary clinical pharmacology

A

Clinical pharmacology applied to veterinary animal species

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7
Q

Evidence based medicine

A

Pharmacological principles based on valid, relevant research and clinical data

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8
Q

What is a Drug

A

Any substance which can affect a biological system.

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9
Q

What is pharmacokinetics

A

ADME
“What the animal does to the drug”
The movement of the drug in the body

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10
Q

What is pharmacodynamics

A

What the drug does to the animal

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11
Q

What are the therapeutic principles?

A

What is being treated
Does the issue need to be treated with a drug
How will the efficacy be monitored

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12
Q

What are the sources of drugs

A

Natural
(Mineral, virus, fungi, bacteria, plant, animal)
Semisynthetic
Synthetic

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13
Q

What are virus’s used for in pharmacology

A
Virus or viral particles for vaccines 
Fly
West Nile
Distemper 
Bovine respiratory syncytial virus
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14
Q

Why are fungis used in pharmacology.

Side note- why did the fungi leave the cool party?

A

BECAUSE THERE WASNT MUSHROOM! Ahhh hahahaha

But really
Antibiotics (pen G from p. Chrysogenum) (cephalosporin C from A chrysogenum)
Antifungals
(Griseofulvin from penicillium griseofulvum)

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15
Q

What is bacterias role in pharmacology

A
Antibiotics
Bacitracin from bacillus subtilis 
Polymixin from b. Polymyxa 
Streptomycin from s. Gruseus
Gentamicin from micromonospora purpurea 

Toxins (for toxoid production)
Tetanus toxin from clostridium tetani

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16
Q

What do plants provide for pharmacology

A
Active ingredients such as:
Alkaloids
Glycosides
Gums
Tannins (2 ns= non nitrogenous)
Fixed oils
Volatile (ethereal) oils (evaporate)
Resins
17
Q

What are alkaloids

A

Compounds containing basic nitrogen atoms, insoluble in water, but the salts are soluble. Bitter taste, can be precipitated by acids. All of the “ine “ suffixes

Atropine
Scopolamine
Morphine
Yohimbine

18
Q

What are glycosides

A

Sugars combined with other organic structures. (Aglycone or genin)

Digoxin
Digitoxin
Ouabain

19
Q

What are gums

A

Polysaccharides excreted by certain trees.
Acacia gum from acacia sp.
Tragacanth from astralagus sp.

20
Q

What are tannins. No this isn’t slang for what you do at the beach!

A

(Non nitrogenous- tested over in vet prep).

Poly phenols that produce astringent effect (precipitate proteins).
-the component that dries the mouth in red wines

21
Q

What are fixed oils

A

Oils that will NOT evaporate when exposed to air!
Cotton seed oil
Castor oil
Linseed oil

22
Q

What are volatile (ethereal) oils

A

Oils that WILL evaporate when exposed to air.
Resins are formed by polymerization of volatile oils.

Peppermint oil
Turpentine oil
Oil of Clove

23
Q

How are resins formed

A

Polymerization of volatile oils

24
Q

What animal products are used in pharmacology

A
Blood
Plasma
Hormones
Toxins
Other
25
Q

What are semisynthetic drugs

A

Drugs from natural sources but undergo chemical treatment.

Amoxicillin
Ampicillin
Apomorphine

26
Q

What are synthetic drugs

A

Compounds completely manufactured in the lab - breaking bad meth its in the ppt.

Sulfonamides
Fentanyl
Furosemide
Acepromazine