Intro-Immune system Flashcards
(24 cards)
How are bacteria dealt with by antibodies?
Opsonization
Which hematopoietic line is adaptive?
Lymphoid precursor
In what time frame does the induced innate immune response act?
4hours - 4 days
What are the two primary lymphoid organs? THe rest are secondary
THymus and bone marrow
How are antigens like bacterial toxins dealt with by antibodies?
they are neutralized by complexes of antibodies binding to them
Plasma cells and effecter T cells are what?
Lymphocytes
What are the 4 challenges pathogens present the immune system with?
1-Form diversity
2-Life cycle diversity
3-Diverse routes of infection
4-Rapid, targeted response over a broad domain
Where are naive lymphocytes activated?
In lymph nodes
antibodies are targeted against many antigens. T/F?
False - a single antigen
Activated B cells are called what and produce what?
plasma cells - produce Antibodies
B lymphocytes are activated through antigen receptor binding by what?
T lymphocytes
*B cell to proliferation and differentiation of B cell to acquire effector function
Neutrophils, eosinophils, mast cells and basophils are what?
Granulocytes
What things are part of the immediate innate immune system?
barriers
antimicrobial peptides
complement system
Rapid response, Limited number of specificities and being constant during response is typical for what response?
Innate immunity
In what time frame does the immediate innate immune response act?
0-4 hours
what is the process called whereby lympocytes that match an antigen proliferate?
clonal selection and expansion
In what time frame does the adaptive e immune response act?
4 days until the defeat of the pathogen, host, or truce
What three cells are primary antigen presenting cells in lymph nodes?
Dendritic cell, Macrophages, B lymphocyte
Slow response, variable, numerous highly selective specificities and improving during response is typical of what response?
Adaptive immunity
CD4 T cells are regulatory and recognize what?
MHC class II and activates B cells(Helper T cell) or macrophages(Th1)
T lymphocytes are co-stimulated through antigen receptor binding by what?
Dendritic cells
*T cell proliferates and differentiates to acquire effector function
Macrophages and dendritic cells are derived from what?
Monocytes
Which hematopoietic line is innate?
Myeloid precursors
CD8 T cells are cytotoxic and recognizes what?
MHC class I and kills infected cells
