Intro Flashcards
pharmacokinetics
body’s effect on drug (distribution, absorption, metabolism and excretion); determines [drug] interacting w receptor
pharmacodynamics
drug’s effect on body; how drugs interact with receptors
terfenadine (seldane)
anti-histamine; antagonist for H1 receptor
receptor
molecular target of drug
prodrug
inactive compound that is activated by metabolism
off-target effects
influence of drug on other receptors
adverse events
undesirable drug effects (on- or off-target effects)
on-target effects
events related to mechanism of drug action
pharmacogenomics
genetic background of patient that affects response to drug
drug interactions
drugs may affect one another adversely
fexofenadine
metabolized form of terfenadine