Intro

Question 0

Where does the milk line running from?

Where can breast tissue develop on the human body

Answer 0

Axilla – >Vulva

Anywhere along the milk line from axilla to vulva

Question 1

Embryologically what exactly is the breast

Answer 1

Modified sweat gland embryologically derived from skin

Question 2

What is the whole structure of the breast

What is the functional unit of the breast?

Answer 2

NiLaMa TLS

Nipple, lactiferous sinus, major duct
Terminal duct, lobules, stroma

Functional unit = terminal duct – lobular unit

Question 3

Explain the layers of the breast epithelium

Answer 3

Lining the ducts and lobules

Inner luminal layer = produce milk

Outer myoepithelial layer = contractile + propel milk

Question 4

Before puberty what does the breast tissue consist of underneath the nipple

Answer 4

Large ducts

Question 5

What is breast development driven by?

Where is breast tissue at its highest density present?
Give another sign that the breast is hormone sensitive?

Answer 5

Oestrogen + progesterone – >
Lobules + small ducts form

Present at upper outer quadrant

During menstrual cycle you get breast tenderness
Hyperplasia during pregnancy
Atrophy after menopause

Question 6

What is galactorrhoea?
Is it a symptom of breast cancer?

Give 2 reasons for galactorrhoea.

Answer 6

Milk production outside of lactation e.g. when not recently pregnant or feeding baby

Not a symptom of breast cancer

Physiological: XS nipple stimulation
Pathological: prolactinoma/drugs – >XS prolactin