Benign Tumours + Fibrocystic Change

Question 0

Macroscopically what do you see me in fibrocystic change

Answer 0

Blue dome appearance

Question 1

What is the most common change in the breast in a pre-menopausal woman?
Presentation?

Answer 1

Fibrocystic change –

lumpy breast/vague irregularity

Question 2

A woman comes in with
premenstrual breast pain.
She says her breast feels LUMPY
and there is FLUCTUATION in the size of the mass. What’s the diagnosis

Answer 2

Fibrocystic change

Question 3

What are the histologic fibrocystic related changes and what are their respective risks for cancer?

Answer 3

Fibrosis/cysts/apocrine metaplasia – no risk= benign
Sclerosing adenosis + ductal hyperplasia - 2x risk
Atypical hyperplasia – 5x risk

Question 4

Where does intraductal papilloma occur in the breast
How does it grow?
Presentation?

Answer 4

Lactiferous sinus

Fingerlike growth lined by both epithelium - epithelial + myoepithelial

Bloody nipple discharge

Question 5

How does one distinguish between intraductal papilloma + papilloma carcinoma

Answer 5

Intraductal papilloma = premenopausal women

Papilloma cancer = old age postmenopausal =
LACK myoepithelial cells

Question 6

What is the most common benign tumour of the breast in premenopausal females?
Features?
What affects the tumour?

Answer 6

Fibroadenoma

Small, well circumscribed, mobile, marblelike

Oestrogen increase e.g. pregnancy/menstruation

Question 7

What is a phyllodes tumour?

Age? Malignancy risk?

Answer 7

Fibroadenoma like tumour with overgrowth of the fibrous component = leaflike projections

Postmenopausal women + increased risk of cancer