Inflammatory Conditions

Question 0

What is a special feature about the lactiferous duct

Answer 0

Highly specialised epithelium

requires vitamin A

Question 1

What causes acute lactational mastitis?
What bacteria causes it?
Treatment?

Answer 1

Breastfeed = stress on skin = fissures on skin ->

Staph aureus enter fissures

Treatment =
continued drainage eg. feeding + DICLOXACILLIN

Question 2

Who usually gets periductal mastitis

Answer 2

Smoker – >vitamin a deficiency – >

Can’t maintain specialised epithelium –>

Columnar – >Squamous metaplasia

Squamous make keratin = block duct = inflammation

Inflammation + repair = SUBAREOLAR mass
Granulation tissue you = Skin retraction

Question 3

Smoking Patient

presents with subareolar mass

with skin retraction

What is the diagnosis?

Answer 3

Periductal mastitis

Question 4

A multiparous post menopausal Patient presents with 
GREEN BROWN NIPPLE DISCHARGE 
With MASSSSSSSSS
What's the diagnosis?
What is seen on histology?

Answer 4

Not breast cancer!!!!!!!!!!!

Mammary Duct Ectasia

Histology = chronic inflammation with plasma cells

Question 5

Explain how fat necrosis of the breast can be picked up

Answer 5

Fat necrosis =
disrupts fat/fibrosis + GIANT cell rxn = MASS!!!!!!!!!!

@Mammogram
Calcium + necrotic fat = calcification = saponification