Intravenous Fluids Flashcards
How is total body water divided?
(60% total mass)
40% Intracellular
20% Extracellular (ISF + Plasma)
Where is extracellular fluid located/
Interstitial fluid
Intravascular fluid
Water in connective tissue
Transcellular fluid
What is osmolality?
Number Osmoles of solute/Kg
How are body fluids measured?
Millimolar concentrations
mosm/kg
What is Osmolarity?
Number Osmoles of solute/L
What is normal plasma osmolarity?
298 (300) mosm/L
What is Tonicity?
Effective Osmolality
Only particles RESTRICTED to one comparment will determine water distribution
Hypotonicity leads to what?
Cellular swelling
Raised ICP
Compromised CBF, herniation
Hypertonicity leads to what?
Cellular dehydration
Venous Sinus thrombosis
How are IV fluid types divided?
Crystalloids
Colloids
What are the colloids?
Gelatins
Starches
Dextrans
Albumin and Blood
Why are crystalloids used?
Cheap
ECF expansion
Why are colloids used?
Anaphylaxis
Coagulopathy
Renal failure
What are the negative effects of 0.9% saline?
Hypercholaemic acidosis
Decreased renal blood flow .’. GFR
Exacerbates sodium retention
What are the ‘balanced’ fluids?
Ringer’s Lactate
Hartmann’s Solution