Intramembranous Ossification

Question 1

Describe Step 1

Answer 1

1) mesenchymal cells migrate and form aggregations in ossification centers. The mesenchymal cells differentiate intoosteoblasts.The osteoblasts produce bone matrix which undergoescalcification.As the osteoblasts become encased in bone matrix they becomeosteocytes.

Question 2

Describe Step 2

Answer 2

2) Bone grows from the ossification centre in linear extensions calledspicules.Blood vessels grow and branch around the spicules to support the bone tissue.

Question 3

Describe Step 3

Answer 3

3) The continued growth at multiple ossifications centers results in the enlargement and fusion of spicules in the trabecular network characteristic ofspongy bone.Further remodeling produces the spongy bone, marrow cavities andcompact bonecharacteristic of mature bone