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3MB Neurology > Intracranial Tumours > Flashcards

Intracranial Tumours Flashcards

1
Q

Primary intracranial neoplasms are the 2nd most common tumours in children. True/False?

A

True

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2
Q

List the typical clinical presentations/symptoms of intracranial neoplasms

A

Neurological deficit
Motor weakness
Headache
Seizures

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3
Q

List clinical presentations/symptoms of raised intracranial pressure

A

Headache
Vomiting
Mental changes
Seizures
Visual impairment

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4
Q

Describe WHO grade I astrocytic tumours

A

Pilocytic
Pleomorphic xanthoastrocytoma

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5
Q

Describe WHO grade II astrocytic tumours

A

Low grade astrocytoma

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6
Q

Describe WHO grade III astrocytic tumours

A

Anaplastic astrocytoma

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7
Q

Describe WHO grade IV astrocytic tumours

A

Glioblastoma multiforme

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8
Q

Who is typically affected by grade I astrocytic tumours?

A

Children
Young adults
Typically headache with vomiting and low appetite

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9
Q

What is the treatment of choice for grade I astrocytic tumour?

A

Surgery (curative)

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10
Q

Grade II astrocytic tumours (low grade astrocytoma) have predilection for which brain lobes?

A

Temporal
Frontal
Parietal

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11
Q

List poor prognostic factors for low grade astrocytomas

A

Age over 50
Focal deficit
Short duration of symptoms
Raised ICP
Altered consciousness

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12
Q

Outline treatment options for low grade astrocytomas

A

Radio/chemo -therapy
Surgery

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13
Q

Which carries poorer prognosis - anaplastic astrocytoma or glioblastoma multiforme?

A

Glioblastoma multiforme (1 year)
Anaplastic astrocytoma (2 years)

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14
Q

List some chemotherapy agents that may be used for astrocytic tumours

A

Temozolamide (CA inhibitor)
Procarbazine
Carmustine wafers

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15
Q

Which lobe do oligodendroglial tumours predominately affect?

A

Frontal lobe

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16
Q

Describe the morphology of oligodendroglial tumours (buzzword)

A

Grayish-pink
Toothpaste-like

17
Q

What is median survival for oligodendroglial tumours?

A

10 years

18
Q

What % of intracranial tumours are meningiomas?

A

20%

19
Q

Majority of meningiomas are asymptomatic. True/False?

A

True

20
Q

What is meningioma en plaque?

A

Subtype of meningiomas that infiltrate dura and sometimes bone
Carpet/sheet-like lesions

21
Q

Meningiomas are usually malignant. True/False?

A

False
Histologically benign (90%)

22
Q

Outline treatment of meningioma

A

Pre-operative embolization
Surgery

23
Q

What do pineal tumours typically obstruct?

A

CSF outflow, leading to hydrocephalus

3MB Neurology (17 decks)

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