Intracellular Signalling

Question 1

Inter-cellular signalling occurs when

Answer 1

a cell surface ligand directly binds to its receptor on the target cell

Question 2

Cytokines are an example of

Answer 2

paracrine signalling

Question 3

Acetyl choline, glutamate, dopamine, noradrenaline and GABA are
all

Answer 3

Neurotransmitters

Question 4

A signal molecule

Answer 4

is a primary messenger

Question 5

An example of a cell surface receptor is the receptor for

Answer 5

glucagon

Question 6

Tyrosine kinase receptors are activated by

Answer 6

Autophosphorylation

Question 7

What do Adaptor proteins associate with?

Answer 7

the ligand receptor

Question 8

cAMP activates

Answer 8

protein kinase A

Question 9

Protein kinase A causes phosphorylation of

Answer 9

serine residues

Question 10

A phosphorylation cascade is when

Answer 10

kinases sequentially phosphorylate other kinases

Question 11

The action of inositol trisphosphate as a second messenger is to

Answer 11

open calcium channels on the endoplasmic reticulum

Question 12

The action of calcium as a second messenger is to activate

Answer 12

calcium-dependent protein kinase

Question 13

Protein kinase C is activated by

Answer 13

DAG

Question 14

cGMP is activated as a second messenger by a signal molecule

binding to

Answer 14

guanylate cyclase

Question 15

Nitric oxide is produced by nitric oxide synthase from

Answer 15

arginine

Question 16

As a second messenger, nitric oxide activates

Answer 16

guanylate cyclase