Intestinal obstruction Flashcards
What is the definition of intestinal obstruction?
Failure of downward passage of intestinal contents
What is meant by dynamic intestinal obstruction?
There is increasing peristalsis working against an obstructing agent
What is adynamic intestinal obstruction?
Peristalsis is absent or ineffective and there are no effective propulsive waves
What is a simple obstruction?
Obstruction of the intestinal lumen without interference with its blodd supply
What happens above the site of obstruction in someone with a simple obstruction?
Peristalsis + distention (due to gas, GI content and fluid build up)
What are causes of death in simple bowel obstruction?
- Fluid & electrolyte imbalance
- Peritonitis
What is strangulation?
Intestinal obstruction with persistent interference of the blood supply
What are causes of intestinal strangulation?
- Strangulated hernia
- Intussuception
- Adhesive intestinal obstruciton
- Volvulus
- Vascular occlusions
What are the pathophysiological consequences of strangulation?
- Venous return is impaired - strangulated bowel and its mesentery look congested
- Serosanguinous fluid formation - accumulated inside the peritoneal cavity
- Arterial supply is impaired - colour of the affected segment becomes black
What are causes of death in strangulation?
- Peritonitis due to perforation
- Hypovolaemic shock
- Sepsis
What is a closed loop obstruction?
When some part of the gut is closed at both ends - THIS IS DANGEROUS
What are causes of small bowel obstruction?
- Adhesions
- Hernias
- Malignant tumours
- Crohn’s disease
- Intussusception
- Gallstone ileus
- Paralytic ileus
- Miscellaneous (bezoars)
What is the most common cause of small bowel obstruction?
Adhesions
What are abdominal adhesions?
Adhesions are bands of ‘scar’ tissue in various degrees of development. They are part of a normal intra-abdominal repair process following a variety of insults
What is the pathophysiology behind abdominal adhesion formation?
Peritoneum is ‘injured’ -> reparative process similar to that seen following the formation or in prevention of a thrombus.
What types of internal hernias can occur which can lead to small bowel obstruction?
- Paraduodenal
- Transmesocolic
- Transmesenteric
- Omental
- Retroanastomotic - bowel is trapped behind a surgical anastomosis
What types of benign tumours of the small intestine can cause SBO?
- Hyperplastic polyps
- Lipomas
- Adenomas - including Peutz-Jeghers polyps
- G/I stromal tumors
- Hemangiomas
What secondary malignancies can present as SBO?
- Ovarian
- Stomach
- Pancreas
- Colonic
- Malignant melanoma
- Lung
- Breast
How can crohn’s disease lead to SBO?
Can cause strictures. May also have adhesions from previous surgeries
What are causes of paralytic ileus?
- Post surgery especially for peritoneal sepsis
- Drugs - TCAs
- Spinal injury
- Electrolyte imbalance - hypokalaemia, hyponatraemia, uraemia
- Extensive handling of the bowel at operation
How does paralytic ileus increase the risk of adhesion formation?
- Intestinal segments have more prolonged contact, which allows fibrous adhesions to form
- Intestinal distention causes serosal injury and ischemia
What are the pathophysiological consequences of small bowel obstruction?
- Proximal dilatation of intestine - due to accumulation of GI secretions and swallowed air
- Stimulation of columnar cell secretory activity - increase in intra-lumenal fluid
- Increased peristalsis above and below the obstruction -
- Early frequent loose stools and flatus
- Increased intraluminal pressure
What is the result of small bowel obstruction in terms of fluid balance?
Hypovolaemia - due to:
- Compression of mucosal lymphatics -> lymphoedema of the bowel wall
- High intraluminal hydrostatic pressures -> increased hydrostatic pressure in the capillary beds
- Massive loss into the third space - fluid, electrolytes, and proteins (into lumen)
- Vomiting + loss of normal fluid intake
How does intestinal obstruction affect intestinal flora?
- Proliferation proximal to obstruction
- Microvascular changes in bowel wall -> Translocation of bacteria to mesenteric lymph nodes
- Resultant bacteraemia
What are symptoms of small bowel obstruction?
- Pain
- Vomiting
- Abdominal distention
- Absolute constipation - late symptom
What are signs of SBO?
- Features on inpection - surgical scars, visible peristalsis
- Dehydration/Signs of shock
- Abdominal distention
-
Bowel sounds
- Increased/borborygmus - early dynamic
- Decreased/absent - paralytic and late mechanical
- May have signs of peritonism
- Empty rectum on PR
- May have herniation - non-reducible
What are the characteristic features of abdominal pain in intestinal obstruction?
Generalized abdominal colicky pain - Each attack lasts for few minuets then gradually disappears, with periouds of relief in between
When is distention less prominent in SBO?
When the obstruction is more proximal
When is distention more prominent in SBO?
In distal obstruction
How does the timing of vomiting roughly indicate where a SBO might be?
The more proximal the obstruction, the earlier vomiting will occur:
- Jejunal Obstruction - Vomiting occurs with the first and each attack of pain
- Ileal Obstruction - Vomiting is delayed for few hours; then it occurs with each attack of pain
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If vomiting occured early on in someone with suspected SBO, what might this suggest about where the problem is in the small intestine?
High - e.g. jejunal obstruction
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If feculent vomiting occured late after someone presented with abdominal pain and marked abdominal distention, where might you suspect the obstruction is occuring?
Low - e.g. ileum
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If someone had jejunal obstruction, how distended would their abdomen be?
Minimally distended
If someone had ileal obstruction, how much abdominal distention might they have?
Prominent central distention
If someone had distention of the flanks, what might this indicate about where the obstruction is occuring?
Colonic distention only - LBO with competent ileocaecal valve
If someone had generalised distention of the abdomen, what might this indicate as to where the obstruction is occuring?
Distended small bowel & colon - LBO with incompetent ileocaecal valve
What featuress would make you think that someone had a stangulated obstruction?
- Pain - more severe and never completely absent in between the attacks
- Shock - usually present and progressive
- Tenderness & Rigidity - Localized tenderness & rebound tenderness
- Tense, tender, irreducible, non-expansile external hernia
What are symptoms of LBO?
- Absolute constipation
- Lower abdominal pain
- Vomiting a late manifestation
-
Features of ischaemia/strangulation
- Acute toxicity
- Fever
- Chills
- Hypotension
- Confusion
What signs can occur in LBO?
- Features on inpection - surgical scars, visible peristalsis
- Dehydration/Signs of shock
- Abdominal distention - Flanks/generalised
- Abdominal Mass
-
Bowel sounds
- Increased/borborygmus - early dynamic
- Decreased/absent - paralytic and late mechanical
- May have signs of peritonism
- Tender LIF - diverticular disease
- Tender RIF +/- mass - impending ischaemia
- PR - rectal mass, blood, mucus
- May have herniation - non-reducible
What are the 2 most common causes of SBO?
Adhesions and hernias
What are causes of large bowel obstruction?
- Colon cancer
- Constipation
- Diverticular stricture
- Volvulus
What investigations would you perform if you suspected intestinal obstruction?
- Bedside - NEWS score, Fluid status and urine output
- Bloods - FBC, U+E’s, LFTs, consider ABG
- Imaging - AXR, Erect CXR, Gastrografin follow through/enema (LBO), Consider CT
What might you see on AXR in someone with suspected small bowel obstruction?
- Dilated loops proximal to the obstruction - predominantly central dilated loops
- Valvulae conniventes are visible
- Air-fluid levels if the study is erect
-
Gasless bowel
- Partial: gas throughout the abdomen and into the rectum.
- Complete: no distal gas, and staggered air-fluid levels.
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What might you see on CXR in someone with an intestinal obstruction?
Free air under the diaphragm - due to perforation
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What is important to include in your examination of someone with features of intestinal obstruction?
PR and hernial orifice exam
What is a gastrografin follow through study?
Involves administration of contrast material into the stomach. The subsequent assessment of degree of passage of this material, using serial x-rays, can provide information regarding the presence and location of the obstruction within the GI tract:
- Partial SBO - medium passes into rectum.
- Complete SBO - medium does not pass into rectum and is held up at site of obstruction.
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What might you find on U+E’s in someone with bowel obstruction?
- Electrolyte imbalance - hyponatraemia, hypokalaemia
- Hyperuraemia - Renal failure
What might you use a gastrografin enema to look for?
Lower bowel obstruction
What might you use a CT to look for in the context of bowel obstruction?
- Confirm the diagnosis if transition point is seen
- Identify the level (SBO/LBO)
- Find the cause
- Staging in obstruction secondary to malignancy
What are causes of obstruction in newborn babies?
- Imperforate anus
- Congenital atresia/stenosis of the gut
- Volvulus
What is the most common cause of obstruction in a child age 3-12 months old?
Intussuception
How would you manage someone with complete/complicated/stangulated SBO?
- ABCDE - give 100% oxygen
- NG decompression
- IV fluids
- Analgesia
- Investigations - AXR, erect CXR, Bloods, monitoring/fluid status
-
Surgery/Emergency surgery - laparoscopy
- Stangulation is an emergency
What are indications for early surgery in bowel obstruction?
- Obstructed hernia
- Suspected strangulation
- Small bowel obstruction in a ‘virgin abdomen’
- Failure of conservative Rx in adhesive SBO
- Obstructing tumours on CT
How would you manage someone with complete/complicated/stangulation obstruction who wasn’t fit for surgery?
- ABCDE
- NG decompression + fluid resus
- Antiemetics
- Antispasmodics
How would you manage partial SBO?
- ABCDE
- NG decompression
- IV fluid resus
- Analgesia
- Anti-emetics
- Consider surgery if not resolved within 48-72 hrs
What are the differences in radiological appearence of the jejunum, ileum and colon?
How would you treat intussusception in an adult?
Laparotomy - resection +/- anastamosis
What are the different types of volvulus that can occur?
- Volvulus neonatorum
- Volvulus of small intestine
- Caecal volvulus
- Sigmoid volvulus
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What are features of a sigmoid volvulus?
- Sudden left sided abdo pain
- Adbo distention
- Absolute constipation
How would you manage a sigmoid volvulus?
- General management
-
Surgery
- Emergency: Untwisting by flexible sigmoidoscopy -> Sigmoid resection in fit patients
- Failed sigmoidoscopy -> open surgery
If someone was found to have a large bowel obstruction on AXR, what investigation would you consider doing next?
Gastrografin enema - determine whether carcinoma, ogilives syndrome or diverticular disease
If someone was found to have free gas under the abdomen on AXR, How would you manage them?
Surgery
What are contraindications for primary anastamosis?
- Poor bowel preparation (on-table lavage *may be indicated)
- Friable bowel
- Circulatory instability
- Synchronous or multiple tumours**
- Peritonitis present
- Immunocompromised patient
- Previous radiation (often pelvic)
- Pelvic abscess present (debatable)
What is OGilvie syndrome?
Clinical syndrome with symptoms, signs & AXR appearance of LBO but with no identifiable mechanical obstruction
What are predisposing factors to developing Ogilivie syndrome?
- Puerperium
- Pelvic surgery
- Trauma
- Cardiorespiratory disorder
- Neurological disorder
How do individuals with Ogilvie syndrome present?
With features of mechanical bowel obstruction
How would you manage Ogilvie syndrome?
- Neostigmine
- Colonoscopic decompression
What are the key things that you need to establish in suspected bowel obstruction?
- Is it small or large bowel?
- Is it dynamic/adynamic (ileus vs mechanical)?
- Is it simple/closed loop/strangulated?
What is the cardinal sign of a strangulated obstruction?
Peristonism
What is the pathophysiology of Ogilvie’s syndrome?
Most likely caused by a disturbance of the autonomic nervous system:
- Reflex sympathetic stimulation inhibiting colon and/or
- Interruption of parasympathetic influence of S2-S4
This leads to colonic dilatation and colonic atony
What mnemonic can be used to remember the main symptoms of obstruction?
PC D+V
- Pain
- Vomiting
- Distention
- Constipation
What mnemonic can be used to remember the causes of small bowel obstruction?
SHAVIT
- Stones (gall stone ileus )
- Hernias (always examine hernial orifices!)
- Adhesions (can occur very early and very late after surgery)
- Volvulus
- Intusssusception / IBD
- Tumour (1º adenocarcinomas rare in small bowel)
**Adhesions and hernias are the commonest causes of small bowel obstruction and should be considered before more unusual causes.