Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Junior Surgery- GI > Chronic Pancreatitis > Flashcards

Chronic Pancreatitis Flashcards

1
Q

What is chronic pancreatitis?

A

Continuing inflammatory disease of the pancreas characterised by irreversible glandular destruction and typically causing pain and/or permanent loss of function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the pathogenesis of chronic alcoholic pancreatitis?

A

Chronic alcoholic pancreatitis is characterised by dilated pancreatic ducts filled with protein plugs which may be calcified due to impaired calcium regulation. This leads to atrophy of the acinar tissue and fibrosis with relative preservation of islets.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are causes of chronic pancreatitis?

A
  • Alcohol
  • Smoking
  • Autoimmune
  • Familial
  • CF
  • Haemochromatosis
  • Pancreatic duct obstruction
  • Congenital - pancreas divisum
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is autoimmune pancreatitis?

A

IgG4-related disorder where the immune system attack the pancreas. There are two types; Type 1 and type 2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are well recognised susceptibility genes implicated in chronic pancreatitis?

A
  • PRSS1
  • SPINK1
  • CFTR
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are symptoms of chronic pancreatitis?

A
  • Epigastric pain boring through to the back - relieved by sitting forward or hot water
  • Bloating
  • Steatorrhoea
  • Weight loss
  • Brittle diabetes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What signs might be seen in chronic pancreatitis?

A
  • Weight loss
  • Erythema ab ignes
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is erythema ab ignes?

A

Erythema caused by exposure to heat - in the context of chronic pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What investigations would you consider doing in someone with suspected chronic pancreatitis?

A
  • Bloods - Serum amylase/lipase, albumin, Ca2+, vit B12, LFTs, Prothrombin time, glucose
  • Ultrasound +/- CT
  • Faecal elastase
  • MRCP/ERCP
  • EUS
  • AXR
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What differential diagnosis would you consider in someone with features of chronic pancreatitis?

A

Pancreatic malignancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What features are you looking for in Endoscopic ultrasound/CT scan?

A

Pancreatic calcification

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

How would you manage someone with chronic pancreatitis?

A
  • Analgesia
  • Pancreatic enzyme replacement - Creon
  • Insulin
  • Dietary advice
  • Surgery
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What dietary advice would you give someone with chornic pancreatitis?

A
  • No alcohol
  • Low fat diet
  • Medium chain triglycerides
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are options for pain relief in chronic pancreatitis?

A
  • Opiates - dihydrocodeine, pethidine
  • Coeliac plexus block
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What surgical procedures are used for unremitting pancreatic pain?

A
  • Pancreatectomy
  • Pancreaticojejunostomy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are complications of chronic pancreatitis?

A
  • Pseudocyst
  • Diabetes
  • Biliary obstruction
  • Local artery aneurysm
  • Splenic vein thrombosis
  • Gastric varices
  • Pancreatic carcinoma

Junior Surgery- GI (43 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions