Intestinal obstruction Flashcards

1
Q

What is the pathophysiology of bowel obstruction?

A
  • Bowel segment gets occluded
  • Gross dilatation of proximal bowel occurs
  • Increase in peristalsis causes secretion of large amounts of fluid rich in electrolytes
  • This is third spacing
  • So urgent fluid resuscitation is needed
  • If obstruction is not relieved there is risk of bowel perforation and peritonitis
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Name 3 causes of bowel obstruction.

A
  • Colonic carcinoma
  • Diverticular disease
  • Sigmoid volvulus
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the two main causes of large bowel vs small bowel obstruction?

A

Large - malignancy, volvulus, diverticular disease

Small - adhesions or hernia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What 4 categories do causes of intestinal obstruction fall into?

A

LIFE categories:

L uminal discontinuity (e.g., atresias)

I nspissated (thickened) luminal contents (as seen in meconium ileus)

F ailure of normal intestinal peristalsis (as seen in Hirschsprung disease)

E xternal compression of the bowel (as seen in volvulus or more rarely, abdominal masses)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

How can you split up the mechanical causes of intestinal obstruction?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Describe the onset of small bowel obstruction vs large bowel obstruction.

A

Small bowel - manifests within hours of onset as the large volume of gastric and pancreaticobiliary secretions builds up

Large bowel - more insidious in onset and delayed by as much as a week

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the clinical features of intestinal obstruction?

A

Vomiting - early in proximal obstruction

  • e.g. semidigested food eaten a day or two earlier = gastric outlet obstruction
  • e.g. bile-stained fluid = upper small bowel obstruction
  • If vomitus becomes thicker and foul-smelling (i.e. faeculent - misnomer as still small bowel content ) = more distal obstruction

Absolute constipation - early in distal obstruction, late in proximal obstruction

Abdominal pain - colicky, mild in uncomplicated obstruction; upper, middle or lower abdominal pain originates in foregut, midgut or hindgut, respectively

Focal tenderness/ guarding/ rebound tenderness - although this should not develop unless there is ischaemia developing

Tympanic sound on percussion - gas rises, flanks will be dull

Auscultation with tinkling bowel sounds - loud and frequent

Dehydration - due to third spacing

Visible peristalsis - only in very thin patients

+/- Hernia - visible in groin with or without strangulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the effects of competence of ileocaecal valve on intestinal obstruction?

A

Competency has an effect on LARGE BOWEL obstruction

Competent ileocaecal valve → no retrograde flow → caecum distends and eventually ruptures (when it reaches 10 cm, it is in imminent danger of rupture)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What might visible peristalsis signify?

A

It is a hallmark of incomplete obstruction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What investigations should you do in bowel obstruction?

A

FBC

Monitor U&Es

VBG - lactate checks for end organ function

Group & save

CT contrast abdo pelvis - 1st line for diagnosis and treatment guidance

NB: AXR still used in some settings.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Summarise the radiological findings in obstruction.

A
  • Small bowel obstruction – Dilated >3cm, central abdominal location, and valvulae conniventes visible
  • Large bowel obstruction – Dilated >6cm, or >9cm if at the caecum, peripheral location, and haustral lines visible
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the management of bowel obstruction?

A

Conservative

  • NBM
  • IV fluids - patients often depleted due to third spacing + urinary catheter + fluid balance chart
  • NG tube if vomiting and gastric contents aspirated
  • Refer to surgeons +/- arrange for surgery within 6hrs if suspecting ischaemia or strangulation
  • Analgesia - opioids e.g. IV morphine sulfate
  • Antiemetics - not prokinetic ones like metoclopramide

Small bowel obstruction:

  • Complicated: Emergency surgery e.g. laparoscopic - if peritonitis, strangulation or bowel ischaemia
  • Uncomplicated: Non-operative for 72hrs - if no resolution of adhesional obstruction, then surgical management

Large bowel obstruction:

  • Conservative - for diverticulitis give abx and fluids, monitoring for complications
  • Flexible sigmoidoscopy - for volvulus
  • Enemas/manual removal - large bowel obstruction caused by faecal impaction
  • Emergency surgery- if perforation
  • Bowel stenting - for malignant cause with palliation only
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is the definitive management of different causes of SBO?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the 3 main types of surgery for LBO?

A

Right hemicolectomy - ileocaecal valve is removed and caecum

Hartmann’s - sigmoid colon is removes with formation of iliac fossa colostomy

Subtotal/total colectomy - for obstructing lesions in descending or sigmoid colon when caecum has torn. Ileosigmoid or ileorectal anastomosis can be done if patient is well enough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the prognosis with bowel obstruction?

A
  • 2/3 uncomplicated cases of obstruction are caused by adhesions
  • these usually resolve in 4days with conservative management
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

A 68-year-old male presents to the surgical assessment unit with a one-week history of increasing abdominal pain and discomfort with constipation. On further questioning he gives a history of alteration in bowel habit and intermittent blood mixed in the stool over the past three months. He has lost ½ stone in weight. He is not taking any medication and has no other history to note.

What is the most likely diagnosis and why?

A

Colorectal malignancy with bowel obstruction - typical or a left sided/rectal carcinoma. No evidence of sepsis or ileus making megacolon, infection and abscess formation unlikely.

17
Q

What is the most likely site of rupture in large bowel obstruction?

A

Caecum - it has the thinnest bowel wall

Law of Laplace

18
Q

Is US useful in obstruction?

A

Ultrasound will be of limited use in the presence of bowel obstruction as gas will degrade the images

More useful investigations:

  • DRE
  • Rigid sigmoidoscopy
  • Erect chest radiograph
  • AXR
  • ECG
19
Q

What does this x-ray show?

A
  • Gross caecal dilatation with loss of haustra - ileocaecal valve is competent
  • T - transverse colon with gas and there is absence of gas on the left side of colon so it can be deduced that the colon is obstructed near the splenic flexure
  • G - gas in the extraperitoneal tissues. This patient had an obstructing carcinoma at splenic flexure and the caecum was perforated.
20
Q

What does this x-ray show?

A
  • Erect film showing multiple loops of dilated small bowel and multiple fluid levels.
  • The obstruction was caused by a small carcinoma of the medial wall of the caecum encroaching upon the ileocaecal valve.

Note: erect abdominal films are rarely taken nowadays

21
Q

What does this AXR show?

A

Large bowel dilatation in keeping with obstruction extending into the pelvis

The large bowel is dilated – note haustrations to identify and peripheral distribution. There is no gas in the rectum making pseudo-obstruction unlikely. No thumb-printing is evident to suggest ischaemia. Note also right hip replacement.

22
Q

What does this x-ray show?

A

Mid small bowel obstruction.

  • Dilated small bowel loops fill the upper left quadrant and centre of the abdomen
  • The small bowel distal to the obstruction is collapsed and is not visible on this film.
  • have valvulae conniventes (plicae circulares [P]) extend across the whole width of the lumen
  • faecal loading of the ascending colon (F)
  • small amount of gas in the sigmoid colon (S) .
  • Note also the metallic tip of the nasogastric tube and the incidental radiopaque gallstone.
23
Q

What happens to the ileocaecal valve after large bowel obstruction?

A

It usually becomes incompetent allowing small bowel to distend and delaying the onset of obstructive symptoms

24
Q

Define pseudo-obstruction.

A

Pseudo obstruction = Ogilvie syndrome in the acute setting; characterised by dilatation of the colon due to an adynamic bowel, in the absence of mechanical obstruction.

Differences:

  • Usually has normal bowel sounds/inaudible.
  • In most cases resolves with conservative measures.
  • Related to e.g. retroperitoneal inflammation, haemorrhage, neurology , biochemical abnormalities, certain drugs (anticholinergics).
25
Q

What is the pathophysiology of pseudo-obstruction?

A

Unknown

May be due to interruption of autonomic nervous system so that there is no smooth muscle action in bowel wall

26
Q

What are the complications of pseudo-obstruction?

A

Toxic megacolon

Bowel ischaemia

Perforation

Therefore must still be managed where possible.

27
Q

What are the causes of pseudo-obstruction?

A
  • Electrolyte imbalance or endocrine disorders
    • Including hypercalcaemia, hypothyroidism, or hypomagnesaemia
  • Medication
    • Including opioids, CCBs, or anti-depressants
  • Recent surgery, severe illness, or trauma
    • Includes MI
  • Neurological disease
    • Includes Pd, MS and Hirschsprung’s disease
28
Q

What are the clinical features of pseudo-obstruction?

A
  • Abdo pain
  • Distension
  • Constipation - or passing abnormal stools, or paradoxical diarrhoea
  • Vomiting - LATE sign

Check for focal tenderness as this is a warning sign of ischaemia

29
Q

What investigations would you do in pseudoobstruction?

A

Bloods:

  • U&Es
  • Ca2+
  • Mg2+
  • TFTs

Imaging:

  • CT contrast (1st line) - must exclude mechanical obstruction
  • AXR - limited for diagnosis as will look the same as in mechanical obstruction so best to do CT contrast

Other:

  • Motility studies e.g. colonic transit time test
  • Colonoscopy +/- biopsy
30
Q

What is the management of pseudo-obstruction?

A

Usually conservative management is sufficient (1-3)

  1. NBM
  2. IV fluids
  3. NG Ryles tube to aid decompression
  4. +/- Endoscopic decompression - done if there is no resolution within 23-48hrs; flatus tube is inserted into the region
  5. +/- Neostigmine IV - anticholinergic trial if still no resolution
  6. +/- Segmental resection +/- anastomosis - or caecostomy or ileostomy
31
Q

List 5 signs that indicate that a patient may need fluid resuscitation urgently.

A
  • SBP <100mmHg
  • HR >90
  • Cold
  • cap refill >2 s
  • RR >20
  • NEWS 5
  • Passive leg raising suggests fluid responsiveness
32
Q

Define closed loop obstruction.

A

Closed loop obstruction is when a single segment of bowel is obstructed at two sites.