Interstitual Lung Disease (P.fibrosis)

Question 1

What is the definition of a Interstitial Lung Disease

Answer 1

Inflammation of lung parenchyma that leads to normal elastic tissue being replaced by stiff scar tissue

Question 2

What are 2 environmental causes of Interstitual lung disease

Answer 2

Smoking

Asbestos

Question 3

What are 2 drugs that can cause Interstitial Lung Disease

Answer 3

Amiodarone

Methotrexate

Question 4

What are 3 diseases that can cause Interstitial Lung Disease

Answer 4

Alpha 1 anti-trypsin deficiency

SLE

RA

Question 5

What are 3 symptoms of Interstitial Lung Disease

Answer 5

SOB
Finger Clubbing
Dry cough >3months

Question 6

What can be heard on auscultation in Interstitial Lung Disease

Answer 6

Fine inspiratory crackles

Question 7

What is the prognosis of Interstitial Lung Disease

Answer 7

very poor

2-5years post diagnosis

Question 8

What drug can be given which is an antifibrotic to slow down Interstitial Lung Disease

Answer 8

Pirfenidone

Question 9

What drug can be given which is a MAB that targets Tyrosine Kinase in Interstitial Lung Disease

Answer 9

Nintedanib