Interpreting personal genomic data

Question 1

What does search for correlation in genes mean?

Answer 1

• correlation between gene and function/disease
• Reverse genetics - from gene to disease/function
• Forward genetics - from disease search for gene

Question 2

QueryOR

Answer 2

• helps in identifying variants

Question 3

What is a genetic disease?

Answer 3

• biological process that does not work because of defetive genes
• gene associated to a disease may not be known
  
  • we may know other genes that are responsible for similar phenotypes
  • causative gene may be among those directly or indirectly associated to similar ones (guilty by association)