Internal and External Solutions

Question 1

Compare the Otrivine and Vicks sinex pump spray. Which spray delivers the most accurate dose?

Answer 1

Vicks sinex pump spray because it is a metered dose so only a certain amount of medicine comes out at each pump, whereas with Otrivine, different amounts of medicine come out each time

Question 2

Which two excipients in the Vicks sinex pump help to prevent bacterial growth and why is it important to prevent bacterial growth?

Answer 2

Benzalkonium - good preservative - increases shelf life
Chlorohexidine gluconate solution - antibacterial
Important to reduce harm to patient

Question 3

What is the likely function of NaOH in Vicks sinex spray and why is it important in nasal preparations?

Answer 3

NaOH is a base and so it will neutralise any acid so prevents stinging in the nasal cavity

Question 4

Which of the excipients is most likely to be the vehicle?

Answer 4

Purified water

Question 5

Which groups of people may have difficulty in administering Hypromellose eyedrops?

Answer 5

Children
Elderly
Patients with nerve damage
Patients with paralysis

Question 6

What is the preservative in Hypromellose eyedrops and why is it important to prevent bacterial growth in medicines?

Answer 6

Benzalkonium chloride - increase shelf life and reduce toxicity
Reduces harm to patients

Question 7

Are there any groups of people that would not be able to use the eye drops due to the addition of the preservative?

Answer 7

Those that are allergic to the ingredient

Question 8

How long can the eye drops be used once opened and why is this?

Answer 8

28 days after opening. Because the eye drops lose their effect and may degrade and become less sterile