Interleuquinas Flashcards

1
Q

IL3

A

PROLIFERACIÓN
Crecimiento de CMPH
Prod: LT
Diana: CMPH

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2
Q

IL7

A

PROLIFERACIÓN
Crecimiento de progenitores linfoides
Prod: celulas estromales M.O.
Diana: progenitores linfoides, LB memoria (supervivencia)

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3
Q

IL5

A

ACTIVACIÓN
Extracelular humoral
Prod: Th2
Diana: eosinófilos

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4
Q

IL4

A

ACTIVACIÓN
Extracelular humoral
Prod: Th2
Diana: LB, macrófagos
Cambio IgE

OJO: también DIFERENCIACIÓN (LT—>Th2)

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5
Q

IL13

A

ACTIVACIÓN
Extracelular humoral
Prod: Th2
Diana: LB, M0, mastocitos
Cambio IgE

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6
Q

IL17

A

ACTIVACIÓN
Extracelular celular
Prod: Th17
Diana: neutrófilos

Induce formacion de proinf (PROINFLAMATORIA)

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7
Q

IL22

A

ACTIVACIÓN
Extracelular celular
Prod: Th17
Diana: neutrófilos

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8
Q

IL2

A

ACTIVACIÓN
Intracelular celular
Prod: Th1
Diana: M0 y LNK

OJO: también DIFERENCIACIÓN (T—>Treg)

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9
Q

IL12

A

DIFERENCIACIÓN
T—>Th1
Prod: M0 y CD
Diana: LT

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10
Q

IL23

A

DIFERENCIACIÓN
T—>Th17
Prod: M0 y CD
Diana: LT

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11
Q

IL1

A

PROINFLAMATORIA
DIFERENCIACIÓN (T—>Th17)

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12
Q

IL6

A

PROINFLAMATORIA
DIFERENCIACIÓN (T—>Th17)

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13
Q

TNFalfa

A

PROINFLAMATORIA

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14
Q

IL10

A

ANTIINFLAMATORIA
ACTIVACIÓN Treg

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15
Q

IL8

A

QUIMIOQUINA

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16
Q

INFa

A

Tipo I
Prod: macrófagos
Aumenta MHC-I

17
Q

INFb

A

Tipo I
Prod: fibroblatos
Aumenta MHC-I

Tto de enf autoinmunes

18
Q

INFg

A

Tipo II
Incrementa MHC-I y II

19
Q

TGFb

A

ANTIINFLAMATORIA

20
Q

BAFF

A

Diferenciación y maduración LB

21
Q

IL15

A

PROLIFERACIÓN
LTc memoria

22
Q

IL11

A

Diferenciación plaquetas

23
Q

IL16

A

Factor quimiotáctico