Anticuerpos Monoclonales Flashcards

1
Q

Basiliximab

A

Anti-CD25
Inmunosupresor (transplantes)

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2
Q

Muromonab

A

Anti-CD3
Inmunosupresor (transplantes)

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3
Q

Rituximab

A

Anti-CD20
Inmunosupresor (linfoma no Hodgkin, AR)

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4
Q

Tracolimus

A

Inhibe transcripción IL-2
Inmunosupresor

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5
Q

Ciclosporina

A

Inhibe transcripción IL-2
Inmunosupresor

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6
Q

Rapamicina/sirolimus

A

Bloquea proliferación IL-2
Inmunosupresor

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7
Q

Abatacept

A

Anti-CD80/86
Inmunosupresor (AR)

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8
Q

Omalizumab

A

Anti Ig-E
Antialérgico (asma, urticaria crónica)

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9
Q

Abciximab

A

Anti-gpIIb:IIIa
Anticoagulante (intervención coronaria)

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10
Q

Ipilimumab

A

Anti-CTLA4
Inmunoestimuldor (melanoma matastásico)

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11
Q

Trastuzumab

A

Anti-HER2/Neu (anti-EGFR)
Cancer de mama

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12
Q

Adalimumab

A

Anti-TNFalfa
Antiinflamatorio

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13
Q

Canakinumab

A

Anti-IL1
Antiinflamatorio

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14
Q

Infliximab

A

Anti-TNFalfa
Antiinflamatorio

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15
Q

Tocilizumab

A

Anti-IL6
Antiinflamatorio

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16
Q

Eculizumab

A

Anti-CD5
Inhibe acción del complemento (hemoglobinuria paroxística nocturna)

17
Q

Pembrulizumab

A

Anti-PD1
Inmunoestimulador (cáncer de pulmón y metátasis)

18
Q

Lanadelumab

A

Calcicreina
Amgioedema hereditario

19
Q

Vendolizumab

A

Integrina a4b7
Chron y colitis ulcerosa

20
Q

Alemtuzumab

A

CD52
EM

21
Q

Certolizumab

A

Anti TNFa

22
Q

Etanercept

A

Anti TNFa

23
Q

Golimumab

A

Anti TNFa