Interleukins Flashcards
1
Q
IL-1 source
A
Macrophages
2
Q
IL-2 source
A
T cells
3
Q
IL-3 source
A
T cells
4
Q
IL-4 source
A
Th2 cells
5
Q
IL-4 source
A
Th2 cells
6
Q
IL-6 source
A
Macrophages
7
Q
IL-8 source
A
Macrophages
T cells
8
Q
IL-10 source
A
Th2 cells
9
Q
IL-12 source
A
Macrophages
10
Q
IL-1 effects
A
Increase neutrophil and macrophage migration
Increase acute phase reactants, fever, and shock
11
Q
IL-2 effects
A
Increase T cell activation and proliferation.
Increase NK cell and macrophage activity
Increase B cell growth
12
Q
IL-3 effects
A
Increase hematopoiesis
13
Q
IL-4 effects
A
Increase Th2 cell differentiation
Increase B cell growth
Increase isotype switching to IgE
14
Q
IL-5 effects
A
Increase differentiation of eosinophils
Increase isotype switching to IgA
15
Q
IL-6 effects
A
Increase T and B cell growth
Increase osteoclastic activity
Increase acute phase reactants and fever
