Interleukins Flashcards
IL-1 source
Macrophages
IL-2 source
T cells
IL-3 source
T cells
IL-4 source
Th2 cells
IL-4 source
Th2 cells
IL-6 source
Macrophages
IL-8 source
Macrophages
T cells
IL-10 source
Th2 cells
IL-12 source
Macrophages
IL-1 effects
Increase neutrophil and macrophage migration
Increase acute phase reactants, fever, and shock
IL-2 effects
Increase T cell activation and proliferation.
Increase NK cell and macrophage activity
Increase B cell growth
IL-3 effects
Increase hematopoiesis
IL-4 effects
Increase Th2 cell differentiation
Increase B cell growth
Increase isotype switching to IgE
IL-5 effects
Increase differentiation of eosinophils
Increase isotype switching to IgA
IL-6 effects
Increase T and B cell growth
Increase osteoclastic activity
Increase acute phase reactants and fever