111 - Autoantibodies Flashcards by Dillon Pryor

Q

Myasthenia gravis

A

Anti-ACh receptor

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Goodpasture syndrome

A

Anti-GBM

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Antiphospholipid syndrome

A

Anti-B₂ glycoprotein

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

SLE

Antiphospholipid syndrome

A

Anticardiolipin

Lupus anticoagulant

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Limited scleroderm (CREST syndrome)

A

Anticentromere

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Pemphigus vulgaris

A

Anti-desmoglein (anti-desmosome)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Type 1 DM

A

Anti-glutamic acid decarboxylase

Islet cell cytoplasmic antibodies

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Bullous pemphigoid

A

Anti-hemidesmosome

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Polymyositis

Dermatomyositis

A

Antisynthetase (e.g., anti-Jo-1)

Anti-helicase (anti-Mi-2)

Anti-SRP

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Hashimoto thyroiditis

A

Antithyroglobulin

Anti-thyroid peroxidase (antimicrosomal)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Primary biliary cirrhosis

A

Antimitochondrial

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Pernicious anemia

A

Antiparietal cell

Anti-intrinsic factor

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Primary membranous nephropathy

A

Antiphospholipase A₂ receptor

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Scleroderma (diffuse)

A

Anti-Scl-70 (anti-DNA topoisomerase I)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Autoimmune hepatitis type 1

A

Anti-smooth muscle

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Sjogren syndrome

A

Anti-SSA

Anti-SSB

(Anti-Ro, Anti-La)

Q

Graves disease

A

Anti-TSH receptor

Q

Lambert-Eaton myasthenic syndrome

A

Anti-presynaptic voltage-gated calcium channel

Q

Celiac disease

A

IgA anti-endomysial

IgA anti-tissue transglutaminase

Q

Microscopic polyangiitis

Eosinophilic granulomatosis with polyangiitis
(Churg-Stauss syndrome)

Ulcerative colitis

A

MPO-ANCA/p-ANCA

Q

Granulomatosis with polyangiitis

(Wegener granulomatosis)

A

PR3-ANCA/c-ANCA

Q

Rheumatoid arthritis

A

Rheumatoid factor (IgM Ab against IgG Fc region)

Anti-CCP (more specific)

Q

Nonspecific screening antibody;

often associated with SLE

A

Antinuclear (ANA)

Q

SLE

A

Anti-dsDNA

Anti-Smith

Drug-induced lupus

Anti-histone

Mixed CT disease

Anti-U1 RNP | (ribonucleoprotein)