111 - Autoantibodies Flashcards by Dillon Pryor | Brainscape

Q

Myasthenia gravis

A

Anti-ACh receptor

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Q

Goodpasture syndrome

A

Anti-GBM

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Q

Antiphospholipid syndrome

A

Anti-B₂ glycoprotein

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Q

SLE

Antiphospholipid syndrome

A

Anticardiolipin

Lupus anticoagulant

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Q

Limited scleroderm (CREST syndrome)

A

Anticentromere

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Q

Pemphigus vulgaris

A

Anti-desmoglein (anti-desmosome)

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Q

Type 1 DM

A

Anti-glutamic acid decarboxylase

Islet cell cytoplasmic antibodies

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Q

Bullous pemphigoid

A

Anti-hemidesmosome

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Q

Polymyositis

Dermatomyositis

A

Antisynthetase (e.g., anti-Jo-1)

Anti-helicase (anti-Mi-2)

Anti-SRP

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Q

Hashimoto thyroiditis

A

Antithyroglobulin

Anti-thyroid peroxidase (antimicrosomal)

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Q

Primary biliary cirrhosis

A

Antimitochondrial

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Q

Pernicious anemia

A

Antiparietal cell

Anti-intrinsic factor

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Q

Primary membranous nephropathy

A

Antiphospholipase A₂ receptor

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Q

Scleroderma (diffuse)

A

Anti-Scl-70 (anti-DNA topoisomerase I)

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Q

Autoimmune hepatitis type 1

A

Anti-smooth muscle

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Q

Sjogren syndrome

A

Anti-SSA

Anti-SSB

(Anti-Ro, Anti-La)

Q

Graves disease

A

Anti-TSH receptor

Q

Lambert-Eaton myasthenic syndrome

A

Anti-presynaptic voltage-gated calcium channel

Q

Celiac disease

A

IgA anti-endomysial

IgA anti-tissue transglutaminase

Q

Microscopic polyangiitis

Eosinophilic granulomatosis with polyangiitis
(Churg-Stauss syndrome)

Ulcerative colitis

A

MPO-ANCA/p-ANCA

Q

Granulomatosis with polyangiitis

(Wegener granulomatosis)

A

PR3-ANCA/c-ANCA

Q

Rheumatoid arthritis

A

Rheumatoid factor (IgM Ab against IgG Fc region)

Anti-CCP (more specific)

Q

Nonspecific screening antibody;

often associated with SLE

A

Antinuclear (ANA)

Q

SLE

A

Anti-dsDNA

Anti-Smith

Q

Drug-induced lupus

A

Anti-histone

Q

Mixed CT disease

A

Anti-U1 RNP

(ribonucleoprotein)