Intercellular Junction Flashcards

1
Q

Tight junction is also caked as _________ & why

A

Zonula occludens
Border of cells are fused together usually along its complete perimeter as a form of a belt

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2
Q

Position of the cell where tight junctions are seen

A

Apical position

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3
Q

Name the proteins seen on tight junction

A

1.occluding
2.Claudins
3.zona occluding
4.actin filament

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4
Q

Name major sites where tight junctions are seen

A

Bbb , git , stomach ,kidney (leaky junction )

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5
Q

What do H pylori and clostridium difficil actually do

A

It attacks or destroy the tight junctions
May lead to peptic ulcer ,diarrhoea etc

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