Intensive Care Cardiology

Question 1

Where are alpha 1 receptors and what is their function

Answer 1

Arteries

Vasoconstriction

Question 2

Where are beta 1 receptors and what is their function

Answer 2

Heart

Positive chronotropy and inotropy

Question 3

Where are beta 2 receptors and what is their function

Answer 3

Arteries

Vasodilation

Question 4

Vasopressin mechanism of action and effect

Answer 4

Arginine vasopressin receptor 1a agonist

Causes pure vasoconstriction

Question 5

Phenylephrine mechanism of action

Answer 5

A1 receptor agonist

Vasoconstriction

Question 6

Noradrenaline mechanism of action

Answer 6

A1, B1 and B2 receptor agonist
Net vasoconstriction
Positive inotropy and chronotropy

Question 7

Dopamine mechanism of action

Answer 7

Dose dependent A1 and B1 receptor agonist. D receptor agonist.
Vasoconstriction and increased chronotropy and inotropy

Question 8

Adrenaline mechanism of action

Answer 8

A1, B1 agonist and mild B2 agonist.
Net vasoconstriction
Positive inotropy and chronotropy

Question 9

Dobutamine mechanism of action

Answer 9

Small A1 agonist and strong B1 and B2 receptor agonist. D receptor agonist.
Increase cardiac output, may decrease BP.

Question 10

Isoprenaline mechanism of action

Answer 10

Pure B1/B2 agonist.

Positive chronotropy and inotropy with vasodilation