Integumentary System Flashcards
Largest System of the Body
Integumentary System
Subcutaneous Layer of the Skin
Hypodermis
4Cell Types of Epidermis
from (Most - Least numerous)
Keratinocytes
Melanocytes
Langerhans Cells
Merkel Cells
Most numerous cell in epidermis and produces keratin?
Keratinocytes
Produce Pigment Melanin
Melanocytes
Pigment Melanin
Yellow - Red
Pheomelanin
Pigment Melanin (brown-black)
Eumelanin
In 4 Cell Types of Epidermis (Macrophage )
Langerhans Cells
Least Numerous in Epidermis
Merkel Cells
Located in Stratum Basale in epidermis where it contacts a sensory neuron called?
Merkel( tactile) disks”
4Layers of Epidermis
Basale
Spinosum
Granulosum
Lucidum
Site of Tonofilament Production
Stratum Basale
Stratum Spinosum
Highest Mitotic Activity of Keratinocytes
Stratum Basale
Deepest Layer of Epidermis
Stratum Basale
2 present in Stratum Basale
Melanocytes
Merkel Cells
Melanin production
Melanocytes
For Touch Sensation
Merkel Cells
Langerhans are present
And Decrease Mitotic Activity of Keratinocytes
Stratum Spinosum
Combination of Stratum Basale and Stratum Spinosum
Stratum Germinativum (aka: Malphigian Layer
Absence of Melanin
Albinism
Deficiency in Melanin
Vitiligo
Amino Acid needed to produce melanin, dopamine,epi,norepi?
Tyrosine
Layers of epidermis where cells are undergoing APOPTOSIS, and No Mitotic Activity
Stratum Granulosum
Layers of epidermis
Absence of Tonofilaments
Stratum Granulosum
2 GRANULES of Stratum Granulosum
Keratohyalin Granules
Lamellar Granules
Converts Tonofilaments to keratin
Keratohyalin Granules
Granules: Layer of Lipid
Lamellar Granules
Found on Thick Skin (fingertips,palms,and soles)
Stratum Lucidum
Clear Cell Layer/ Translucent Layer
Stratum Lucidum
Mechanoreceptor for light Touch
Meissner Corpuscle
Thyroid Hormones that is More POTENT
T3 -Triodotyronine
Thyroid Hormones that is More NUMEROUS
T4 -Thyroxine
Decrease conversion of phenylalanine to thyroxine
Phenylketonuria
Abnormal thickening of Stratum Corneum due to constant friction
Callus
Excess keratinocytes shedding from Scalp
Dandruffs
SCALP
Skin C.T Aponeuroses L.C.T Periosteum
Keratinocytes divides and move more quickly than Normal
Psoriasis
Psoriasis signs and symptoms
SMA
Silvery scales
Monroe’s Abcess
Auspitz Sign
Abnormal keratin production
Silvery Scales
Cardinal Sign of PSORIASIS
Monroe’s Abcess
Bleeding Spots in Psoriasis
Auspitz Sign
Thicker than epidermis and Provides Blood Supply for Epidermis
Dermis
2Layers of Epidermis
Papillary Layer
Reticular Layer
Layers of Epidermis (Thinner Layer)
Papillary Layer
Extension of Dermis papunta kay Epidermis
Dermal Papillae
Nipple Projections towards Epidermis
Dermal Papillae
Epidermal Extensions towards Dermis
Rete Pegs/Epidermal Ridges
Disease associated w/ SAW-TOOTH like Rete-Pegs
Lichen Planus
Thicker than Papillary Layer
Reticular Layer