Integumentary System Flashcards

0
Q

What part of hair structure contains a vascularized papilla of loose connective tissue for nourishing stem cells of the hair matrix layer

A

Hair papilla

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1
Q

Graying of hair due to loss of what enzyme?

A

Tryosinase which produces hair color

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2
Q

Hair bulb contains two types of cells namely

A

Melanocytes and keratinocytes

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3
Q

Increase in the length of hair shaft is done by?

A

Internal root sheath layer of hair bulb

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4
Q

The hair shaft has three layers namely?

A

Cuticle - dead overlapping cells
Cortex - keratinization portion of hair with melanosomes
Medulla - found only in thick hair (terminal hair)

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5
Q

The Growing phase of hair, where 85% of hair stays between 2-5 years is called

A

Anagen

**Hair Growth Cycle Mnemonic: ACT

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6
Q

Involuting phase of hair growth cycle that lasts 3-6 weeks is called

A

Catagen

**Hair Growth Cycle Mnemonic: ACT

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7
Q

Resting phase of hair growth, where 15% of hair rests for 3-5 months is called

A

Telogen

**Hair Growth Cycle Mnemonic: ACT

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8
Q

What region of eccrine sweat glands have stratified cuboidal epithelium cells and appears dark stained

A

Sweat Duct region/ excretory region

  • *Forms interpapillary peg in papillary layer
  • *Clue: D - dark, D - duct
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9
Q

What region of the eccrine sweat gland has simple to stratified cuboidal epithelium and stains light

A

Secretory region

**Can be surrounded by myoepithelial cells

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10
Q

Fingernail is made up of what in the stratum corneum? And what is the name of the nail region that produces it?

A

Hard keratin, produced in nail matrix, contains cuticle, nail plate and nail bed.

** Nail cuticle _ eponychium (softer keratin)
Hyponychium- front side

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11
Q

Pilosebaceous unit is made up of

A

Hair follicle (shaft, bulb & papilla), sebaceous gland and arrector pili muscle

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12
Q

Terminal hair is found in three places namely

A

Scalp, axilla, pubic area

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13
Q

Thin silky hair all over the body is called?

A

Vellus hair

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14
Q

Merkel cells are found only in what type of skin?

A

Basal layer of Thick skin

**Clue: merKel, thicK skin

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15
Q

Melanocytes are found in what type of skin

A

Basal layer of ThiN skin

**Clue: MelaNocytes

16
Q

Langerhans cells are found in all types and layers of what type of skin cells

A

Non-keratinizing stratified epithelium

17
Q

Hemidesmosomes in basal layer of skin act to:

A

Connect cells to basement membrane

18
Q

Desmosomes found in spinosum layer act to:

A

Resist distortion
Connect to tonofilaments
Hold cell cytoplasm together

19
Q

All cell layers have keratinocytes but in different states namely:

A
  1. Basal layer - stem cells
  2. Spinosum - producing tonofilaments and lamellar bodies
  3. Granule sum - flattened (squamous), accumulation of keratohyalin granules and lamellar granules released
  4. Lucidum - dead flattened cells, no organelles, filled with keratin
  5. Corneum - dead flattened cells called squames, filled with keratin and desquamation occurs
20
Q

Melanin is usually present in the spinosum layer and lost in which layer?

A

Granulosum

21
Q

There are two forms of Keratinocytes, namely:

A

Tonofilaments and keratohyalin granules

22
Q

Melanocytes produce melanin, describe the process

A

Tyrosine –> DOPA –> melanin via tyrosinase

Tyrosinase is made in the RER, sent to Golgi, hops on melanosome vesicles and is activated by UV