Integumentary System Flashcards
What part of hair structure contains a vascularized papilla of loose connective tissue for nourishing stem cells of the hair matrix layer
Hair papilla
Graying of hair due to loss of what enzyme?
Tryosinase which produces hair color
Hair bulb contains two types of cells namely
Melanocytes and keratinocytes
Increase in the length of hair shaft is done by?
Internal root sheath layer of hair bulb
The hair shaft has three layers namely?
Cuticle - dead overlapping cells
Cortex - keratinization portion of hair with melanosomes
Medulla - found only in thick hair (terminal hair)
The Growing phase of hair, where 85% of hair stays between 2-5 years is called
Anagen
**Hair Growth Cycle Mnemonic: ACT
Involuting phase of hair growth cycle that lasts 3-6 weeks is called
Catagen
**Hair Growth Cycle Mnemonic: ACT
Resting phase of hair growth, where 15% of hair rests for 3-5 months is called
Telogen
**Hair Growth Cycle Mnemonic: ACT
What region of eccrine sweat glands have stratified cuboidal epithelium cells and appears dark stained
Sweat Duct region/ excretory region
- *Forms interpapillary peg in papillary layer
- *Clue: D - dark, D - duct
What region of the eccrine sweat gland has simple to stratified cuboidal epithelium and stains light
Secretory region
**Can be surrounded by myoepithelial cells
Fingernail is made up of what in the stratum corneum? And what is the name of the nail region that produces it?
Hard keratin, produced in nail matrix, contains cuticle, nail plate and nail bed.
** Nail cuticle _ eponychium (softer keratin)
Hyponychium- front side
Pilosebaceous unit is made up of
Hair follicle (shaft, bulb & papilla), sebaceous gland and arrector pili muscle
Terminal hair is found in three places namely
Scalp, axilla, pubic area
Thin silky hair all over the body is called?
Vellus hair
Merkel cells are found only in what type of skin?
Basal layer of Thick skin
**Clue: merKel, thicK skin
Melanocytes are found in what type of skin
Basal layer of ThiN skin
**Clue: MelaNocytes
Langerhans cells are found in all types and layers of what type of skin cells
Non-keratinizing stratified epithelium
Hemidesmosomes in basal layer of skin act to:
Connect cells to basement membrane
Desmosomes found in spinosum layer act to:
Resist distortion
Connect to tonofilaments
Hold cell cytoplasm together
All cell layers have keratinocytes but in different states namely:
- Basal layer - stem cells
- Spinosum - producing tonofilaments and lamellar bodies
- Granule sum - flattened (squamous), accumulation of keratohyalin granules and lamellar granules released
- Lucidum - dead flattened cells, no organelles, filled with keratin
- Corneum - dead flattened cells called squames, filled with keratin and desquamation occurs
Melanin is usually present in the spinosum layer and lost in which layer?
Granulosum
There are two forms of Keratinocytes, namely:
Tonofilaments and keratohyalin granules
Melanocytes produce melanin, describe the process
Tyrosine –> DOPA –> melanin via tyrosinase
Tyrosinase is made in the RER, sent to Golgi, hops on melanosome vesicles and is activated by UV