integumentary system Flashcards

1
Q

what is the skin?

A
  • organ: different tissues working together
  • largest organ in the human body
  • 7% of total body weight
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2
Q

what are the functions of the skin?

A
  • protection against mechanical damage
  • prevent water loss
  • vitamin d production
  • sensory reception
  • temperature regulation
  • excretion of salts/waste
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3
Q

what is the epidermis?

A
  • keratinized stratified squamous epithelium
  • 4 cell types
  • avascular
  • regenerates every 35-45 days
  • 4 or 5 cell layers (thin vs. thick)
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4
Q

what are the 4 types of cells in the epidermis?

A
  • keratinocytes: produce keratin, most abundant
  • melanocytes: produce melanin to shield from UV
  • merkel cell: sensation
  • dendritic cell: immune cell
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5
Q

what are the layers of the epidermis? (superficial to deep)

A
  • stratum coreneum
  • stratum lucidum
  • stratum granulosum
  • stratum basle
  • dermis
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6
Q

what is the dermis?

A
  • underlies epidermis
  • strong, flexible connective tissue
  • highly vascularized
  • innervated (sensation)
  • 2 cell layers: papillary (20%), reticular (80%)
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7
Q

describe the layers of the dermis

A
  • papillary layer: superficial, about 20%. areolar connective tissue, provides nutrients to epidermis, dermal papillae increase surface area for transport of material into epidermis
  • reticular layer: deep, about 80%. mostly dense irregular tissue. network of collagen and elastic fibers provide stretch, strength
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8
Q

what is the hypodermis (subcutaneous)?

A
  • supports skin (epidermis and dermis)
  • areolar and adipose loose connective tissue (mostly adipose)
  • stores fat
  • provides insulation
  • anchors skin to muscles
  • allows movement of skin over muscle and bones
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9
Q

what are fingerprints?

A

dermal papillae push up and elevate the overlying epidermis (create epidermal ridges). patterns are unique

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10
Q

what is hair?

A
  • flexible strands made of keratin
  • pigement comes from melanocytes
  • functions: sensation (light touch), protection, insulation
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11
Q

what are nails?

A
  • modified stratum corneum
  • protects the fingers
  • parts: free edge (white), nail body, nail root (embedded in skin)
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12
Q

describe the structure of a hair follicle

A
  • basic: shaft (exposed), root (embedded)
  • hair follicle: bulb (innervation), papilla (blood supply)
  • arrector pili muscle: contraction of this muscle raises (erects) hair, causes goosebumps
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13
Q

what are sweat glands?

A
  • sweat glands can be eccrine (a form of merocrine gland) or apocrine
  • eccrine sweat glands: secreted onto skin surface. allows evaporating cooling
  • development: invaginate from skin surface
  • product: 99% water, 1% salts/wastes
  • acidic; antibacterial properties
  • apocrine sweat glands discharge into hair follicles, not body surface
  • development: outgrowths from hair follicles
  • product: complex molecules, odorous, found in armpits/genitals
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14
Q

what is a modified sweat gland?

A
  • ceruminous: line external ear canal, produce earwax
  • mammary: secrete milk
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15
Q

what is a sebaceous gland?

A
  • multicellular exocrine glands
  • open into hair follicles
  • secrete sebum (oil): holocrine secretion-cells accumulate sebum and burst to release product
  • moisturizes hair and skin
  • blocked hair follicle = acne
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16
Q

what is melanin?

A
  • melanin acts as a natural sunblock, determines skin tone
  • number of melanocytes does not vary among individuals; activity level of melanocytes does
17
Q

what is the correlation between skin color and UV?

A
  • some exposure to sunlight is essential: uv rays cause epidermis to produce vitamin d, needed for absorbing calcium (light skin in the north facilitates this)
  • excessive exposure is dangerous: reduces folate levels needed for embryonic development, promotes skin cancer
  • skin color affects amount of uv absorbed: darker skin in tropical (high sun) environment reduces uv absorption, protects folic acid levels
18
Q

what is skin cancer?

A

most common form of cancer
- basal cell carcinoma originates in the stratum basale. metastasis is rare
- melanoma is potentially life-threatening, because cancerous melanocytes grow rapidly and spread through the lymphatic system

19
Q

what are the ABC’s of skin cancer?

A
  • a: asymmetry
  • b: border
  • c: color
  • d: diameter
  • e: elevation