Integumentary System Flashcards
Integument
skin
Dermatology
study of skin
Epidermis
keratinized, stratified squamous epithelium, superficial
Dermis
deeper layer, primarily dense irregular CT (proper CT);
2 layers:
papillary
deeper reticular
Hypodermis (subcutaneous layer)
deep to dermis; layer of areolar and adipose CT; not apart of integumentary system
Layers of epidermis (deep to stratified)
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum
Stratum basale (basal layer)
deepest epidermal layer; germinative layer; single layer of cells;
Cell Types:
Keratinocytes (living cells)
Melanocytes
Tactile cells
Keratinocytes
most abundant cells in epidermis, divide to regenerate new cells, replace old cells shed at surface; synthesizing of keratin
Keratin
protein that strengthens epidermis and makes skin almost waterproof
Melanocytes
scattered among keratinocytes; produces and stores melanin in response to UV light; transfer pigment granules (melanosomes) into keratinocytes; shields nuclear DNA from UV radiation
melanosomes
packaged melanin; the pigment accumulates around nucleus of keratinocytes
Tactile Cells (merkel cells)
few; sensitive to touch; when compressed release chemicals to stimulate sensory nerve endings
Stratum spinosum
several layers of keratinocytes; daughter cells from stratum basale
Epidermal Dendritic cells (langerhans cells)
branching extensions; initiate immune response; phagocytosis cells; responsive to pathogens and epidermal cancer cells
Stratum granulosum
3-5 layers of keratinocytes; beginning of keratinization, producing keratin but not enough that it is still alive, nucleus and organelles start to disintegrate
Stratum lucidum
2-3 layers, translucent; only on thick skin on palms and soles; transparent because of intermediate product in maturation of keratin; composed of dead skin cells
Stratum corneum
most superficial, 20-30 layers of dead skin; cells are anucleste and tightly packed; dry surface protects and is unsuitable for microorganism growth; about 2 weeks then shed
anucleate
without a nucleus
Migration of keratinocytes
originate from stem stem cells in stratum basale
migrates through strata to stratum corneum (2 weeks)
undergoes structural changes
Thick Skin
palm of hands and soles of feet; all 5 layers of epidermal strata; sweat glands; no hair follicles or sebaceous glands
Thin Skin
covers most of body; lacks stratum lucidum; contains sweat glands, hair follicles, and sebaceous glands
Papillary layer
superficial region; areolar CT; consists of dermal papillae
Dermal papillae
projections of the dermis
Epidermal Ridges
projections of epidermis; interlocking arrangement with the dermal papillae
Reticular Layer
most of the dermis, dense irregular CT; deeper portion; large bundles of collagen fibers
Contributions to skin color
hemoglobin, carotene, and melanin
Hemoglobin
oxygen binding protein in red blood cells; gives blood vessels reddish tint
Carotene
accumulates in subcutaneous fat and keratinocytes of stratum corneum; yellow-orange pigment