Integumentary System Flashcards
Integument
skin
Dermatology
study of skin
Epidermis
keratinized, stratified squamous epithelium, superficial
Dermis
deeper layer, primarily dense irregular CT (proper CT);
2 layers:
papillary
deeper reticular
Hypodermis (subcutaneous layer)
deep to dermis; layer of areolar and adipose CT; not apart of integumentary system
Layers of epidermis (deep to stratified)
Stratum basale
Stratum spinosum
Stratum granulosum
Stratum lucidum
Stratum corneum
Stratum basale (basal layer)
deepest epidermal layer; germinative layer; single layer of cells;
Cell Types:
Keratinocytes (living cells)
Melanocytes
Tactile cells
Keratinocytes
most abundant cells in epidermis, divide to regenerate new cells, replace old cells shed at surface; synthesizing of keratin
Keratin
protein that strengthens epidermis and makes skin almost waterproof
Melanocytes
scattered among keratinocytes; produces and stores melanin in response to UV light; transfer pigment granules (melanosomes) into keratinocytes; shields nuclear DNA from UV radiation
melanosomes
packaged melanin; the pigment accumulates around nucleus of keratinocytes
Tactile Cells (merkel cells)
few; sensitive to touch; when compressed release chemicals to stimulate sensory nerve endings
Stratum spinosum
several layers of keratinocytes; daughter cells from stratum basale
Epidermal Dendritic cells (langerhans cells)
branching extensions; initiate immune response; phagocytosis cells; responsive to pathogens and epidermal cancer cells
Stratum granulosum
3-5 layers of keratinocytes; beginning of keratinization, producing keratin but not enough that it is still alive, nucleus and organelles start to disintegrate