integumentary Flashcards

1
Q

Keratinocytes

A

the most dominant cell type constituting the epidermis, keratinocytes play multiple roles essential for skin repair. They are the executors of the re-epithelialization process, whereby keratinocytes migrate, proliferate, and differentiate to restore the epidermal barrier. They originate in the deepest layer of the epidermis, the stratum basale and move up to the final barrier layer of the skin, the stratum corneum.

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2
Q

Melanocytes

A

a mature melanin-forming cell, especially in the skin. in the layer of basal cells at the deepest part of the epidermis.

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3
Q

Papillary dermis

A

The thin top layer of the dermis (the inner layer of the skin). The papillary dermis has connective tissue and blood vessels that give nutrients to the epidermis (the outer layer of the skin) and that help control the temperature of the skin.deep to the epidermis

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4
Q

Reticular dermis

A

The thick bottom layer of the dermis (the inner layer of the skin). The reticular dermis has blood vessels and connective tissue that supports the skin. Hair follicles, oil and sweat glands, and other structures are also found in the reticular dermis.

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5
Q

langerhans cells

A

reside in the epidermis as a dense network of immune system sentinels. These cells determine the appropriate adaptive immune response (inflammation or tolerance) by interpreting the microenvironmental context in which they encounter foreign substances.

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6
Q

tactile epithelial cells

A

Merkel cells, also known as Merkel-Ranvier cells or tactile epithelial cells, are oval-shaped mechanoreceptors essential for light touch sensation and found in the skin of vertebrates

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7
Q

stratum granulosum

A

(or granular layer) is a thin layer of cells in the epidermis lying above the stratum spinosum and below the stratum corneum (stratum lucidum on the soles and palms). Keratinocytes migrating from the underlying stratum spinosum become known as granular cells in this layer.

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8
Q

stratum corneum

A

the outermost layer of the epidermis and marks the final stage of keratinocyte maturation and development. Keratinocytes at the basal layer of the epidermis are proliferative, and as the cells mature up the epidermis, they slowly lose proliferative potential and undergo programmed destruction.

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9
Q

stratum lucidum

A

2-3 cell layers, present in thicker skin found in the palms and soles, is a thin clear layer consisting of eleidin which is a transformation product of keratohyalin.

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10
Q

stratum basale

A

stratum germinativum, is the deepest layer, separated from the dermis by the basement membrane (basal lamina) and attached to the basement membrane by hemidesmosomes.

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11
Q

stratum spinosum

A

8-10 cell layers, also known as the prickle cell layer contains irregular, polyhedral cells with cytoplasmic processes, sometimes called “spines”, that extend outward and contact neighboring cells by desmosomes. Dendritic cells can be found in this layer.

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12
Q

epidermis

A

the surface epithelium of the skin, overlying the dermis.

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13
Q

dermis

A

the thick layer of living tissue below the epidermis which forms the true skin, containing blood capillaries, nerve endings, sweat glands, hair follicles, and other structures.

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14
Q

hypodermis

A

the bottom layer of skin in your body. It has many important functions, including storing energy, connecting the dermis layer of your skin to your muscles and bones, insulating your body and protecting your body from harm. As you age, your hypodermis decreases in size, and your skin starts to sag.Oct 19, 2021

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15
Q

adipose tissue

A

otherwise known as body fat, is a connective tissue that extends throughout your body. It’s found under your skin (subcutaneous fat), between your internal organs (visceral fat) and even in the inner cavities of bones (bone marrow adipose tissue).

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16
Q

eccrine gland

A

A type of simple sweat gland that is found in almost all regions of the skin. These glands produce sweat that reaches the surface of the skin by way of coiled ducts (tubes). The body is cooled as sweat evaporates from the skin.

17
Q

apocrine galnd

A

in the skin and eyelid are sweat glands. Most apocrine glands in the skin are in the armpits, the groin, and the area around the nipples of the breast. Apocrine glands in the skin are scent glands, and their secretions usually have an odor.

18
Q

sebaceous gland

A

a small gland in the skin which secretes a lubricating oily matter (sebum) a sticky oily substance the body produces in order to keep the skin moisturised. It’s made up of a collection of fat molecules, waxes, and squalene.into the hair follicles to lubricate the skin and hair.