Integument Flashcards
Layers of skin
epidermis, dermis, hypodermis (not actually part of skin)
Examples of integument
Skin, glands, scent glands, hair, claws, hooves, feathers, horns, antlers, mammary glands, anal sacs, wound healing
Functions of skin
Protection from dehydration (waterproofing) and infection (physical barrier), sensory, excretion (sweat gets rid of metabolic waste), regulation of temperature, absorption of UV
epidermis
keratinized stratified squamous epithelium, avascular, receives blood supply from dermis, melanocytes, dendritic cells, merkel cells
dermis
Blood supply, relatively acellular, mostly ECM dense irregular connective tissue
hypodermis
loose connective tissue, superficial fascia, anchors dermis to underlying muscle/bone
adipose tissue
fat pad (structural fat), foot pads
types of epidermis
thick skin and thin skin, again based on epidermis layers not the other layers
Layers of epidermis
(thick skin) stratum basale, stratum spinosum, stratum granulosum, stratum lucidum, stratum corneum
Thick skin
glabrous, no hair follicles, 5 identifiable epidermal layers, merocrine sweat glands
Thin skin
nonglabrous, has hair follicles, thin stratum corneum, stratum lucidum, and granulosum can be hard to define, apocrine sweat glands
stratum basale
cell division (stem cells give rise to keratinocytes) sits on basement membrane, melanocytes, merkel cells (touch sensors)
stratum spinosum
cells attached by desmosomes, spiky appearance because desmosomes stay in place as cell dehydrates
membrane coating granules help produce lipids
keratinization begins here
stratum granulosum
cells still have nuclei
keratohyalin granules
stratum lucidum
only in thick skin
lack organelles and nuclei
keratin filaments
This layer may not be present in thick skin
stratum corneum
further from surface, stil have desmosomes
Closer to surface the desmosomes breakdown, then desquamated
stratum disjunctum
stratum corneum being desquamated/ sloughed off
Melanocytes
neural crest derived
located in the basal layer
Source of melanin (pigment) for keratinocytes
Also found in the external root sheath and matrix of hair
How does melanin protect from UV light?
Picked up by keratinocytes and becomes more concentration at the center of cell to protect the DNA
keratinocytes
spiky/hairlike projections of cytoplasm
Dendritic cells
langerhans cells, macrophages, Antigen Presenting Cells
don’t show in routine staining
Ingests foreign particle to present to immune system
Merkel cells
light touch receptors, slow-adapting, located in the basal region
Dermis
Papillary and reticular layers
Papillary layers
dermal ridges, loose connective tissue, anchoring fibrils from basal lamina of epidermis
reticular layer
dense irregular connective tissue (Type I collagen and elastin)
Sweat glands, hair follicles with arrector pili muscles (smooth muscles),
mechanoreceptors, blood and lymph vessels
Only dermal layer present in thin skin.