integument Flashcards
basale layer of epidermis
Stratum Germinativum
Cells occupying the Stratum Germinativum
Melanocytes, Langerhans, Merkel
purpose of melanin
protects DNA of germinal cells of stratum gerinativum
function of Langerhans cells
antigen presentation - they migrate through the dermis to lymph nodes and interact with helper T cells
the layers of the epidermis from bottom to top
germinativum, spinosum, granulosum, lucidum, corneum
what cell type is partcular to the spinosum
prickle cells anchored to one another by tonofilaments making tonofibrils called prekeratin. Prickle cells distribute tesile stress.
function of Merkel cell
paracrine mechanorececptors. may migrate up to spinosum. associate with free nerve endings of cutaneous sensory receptors
keratohyalin
soft keratin mixed with a few other proteins that cause the granulosum to stain basophilic
which layer is only predominant in thick skin
lucidum.
cells that occupy lucidum
dead keratinocytes filled with keratin filaments and a few organelles
Psoriasis
extreme turn over of keratinocytes (a week) do not allow cohesive corneum layer
what layer is most noticeable in thick skin
corneum
what is the specific tissue of dermis
dense irregular CT
Rete pegs
epidermal reaching into the dermis
Papillae
dermis projections into the epidermis
3 components of the DE Junction
hemidesmosomes, basalamina, CT fibers (collagen type 1)
2 layers of the dermis
papillary loose CT (more collagen type 3, capillary loops), reticular dermis dense irregular CT (more collagen type 1, capillary and nerve networks)