Integument Flashcards
When would you use a unna boot?
For a venous ulcer to unload the wound
where is the thickest skin in the body?
palms of hand and sole of foot, contains stratum lucidum
what is excreted with sweat and why is that important?
Urea and salt, which aids in elimination of metabolic waste
layers of epidermis from superficial to deep
stratum corneum, lucium
granulosum, spinosum, basale
what cells can you find in statrum granulosum
live keratinocytes and langerhans cells for immunity
what is found in stratum spinosum
ketatinocytes and langerhans
what cells are found in the stratum basale
merkel cells, melanocytes, epidermal cells
what is found in the dermis
collagen, elastin, mucopolysaccharide matrix, lymph, bv, nerves and nerve endings, hair follicles, sebaceous and sweat glands, fibroblasts, macrophages lymphocytes, mast cells
what types of glands are sebaceous glands and what is the function of sebum
exocrine, defends against bacteria and fungus
where are apocrine sweat glands and when are the stimulated
found in axillary and genital regions, activated with stress
superficial or partial thickness wounds occur in what layer of skin
epidermis
do we want wounds wet or dry
wet
within 10 to 15 minutes of a dermal wound what happens
initial vasoconstriction to reduce blood loss and decrease risk of infection, fibrin plug created, this is called homeostasis
what occurs in the inflammatory phase of healing and how long is this phase
24-48 hours, rubor, calor, swelling, pain, loss of function, vasodilation from non-injured vessels occur to bring leukocytes and growth factors for healing.
what happens at the end of the inflammatory phase
Phagocytosis and neovascularization
key cells in the inflammatory phase of healing
mast cells, platelets, leukocytes, macrophages–> can be impaired by diabetes
4 primary events of granulation/proliferative phase
- angiogenesis
- granulation formation
- wound contraction
- epithelialization
primary cells of granulation phase
myofibroblasts for wound contraction
fibroblasts for collagen, elastin and glycosaminoglycan production
epithelial cells for epithelialization
maturation/matrix formation phase: time after injury and what happens
begins 2-4 weeks after injury and can last for years
continued collagen synthesis and alignment
normal scar formation
pink, bright for 6-12 weeks then lavender to soft pink for 12-15 moths which will finally flatten and turn white
how can you reduce hypertrophic or kelloid scarring
compression garments, silicon gels/sheets
what can delay wound healing
advanced age
impaired oxygenation
poor nutrition
comorbidities
wound bioburden
infection
stress
disease
medications
cool temperatures
iatrogenic (pressure, shear forces)
smoking
what will infection and increased wound bioburden do to phases of healing
prolong the inflammatory phase
stress effect on wounds
decreases pro inflammatory cytokines and increases wound hypoxia