Integrated

Question 1

Kid comes in with itchy asshole. Which drug treatment works by causing spastic contractions of parasitic muscles?

Answer 1

Pyrantel

Question 2

An expecting mother and her 6 year-old child come in with itchy assholes. What drug is usually safe for the child, but has shown to be embryotoxic in pregnant rats?

Answer 2

Albendazole…probably better than mebendazole in this case due to the migratory pattern

Question 3

A kid comes in after having bloody diarrhea and barrel-shaped eggs are found in his stool. What are the drug options

Answer 3

Albendazole/mebendazole are the big ones

Ivermectin can be added

She mentioned that levamisole could be used, but it wasn’t mentioned on DynaMed

Question 4

A patient comes in with abdominal pain, an ultrasound shows giant roundworms. How should this be treated?

Answer 4

Albendazole/mebendazole

Ivermectin

Question 5

A young kid comes in with a rash on his thighs and butt and has had some bell pain. What is the MoA of the best treatment option to treat the parasite infection?

Answer 5

Activation of glutamate-gated chloride channels (Ivermectin)

Question 6

The pig farmer who likes rare pork needs treatment for his infection. What is the MoA of the best treatment option?

Answer 6

Opening of divalent cation channels (Praziquantel)

Question 7

The sheep farmer who has an interesting infection needs treatment. What two drugs are recommended? What else is commonly done?

Answer 7

Albendazole or praziquantel

Surgical drainage

Question 8

A patient comes back from the Boundary Waters and has really bad smelling diarrhea. You prescribe the medication and recommend that the patient refrains from alcohol. What drug did you prescribe?

Answer 8

Metronidazole or Tinidazole

Question 9

A young immunocompetent kid comes in with a 2-week history of diarrhea after being at a water park. The mother will not leave without a prescription…despite best efforts to avoid medicating. What is the MoA of the prescribed drug?

Answer 9

Interferes with pyruvate::ferrdoxin oxidoreductase enzyme…interferes with the bugs anaerobic energy metabolism

Question 10

A patient comes in with mucussy/bloody diarrhea…she has amebic dysentery. What should be prescribed?

Answer 10

Metronidazole or tinidazole