Insulin Resistance Flashcards
1
Q
What does insulin do?
A
It is a small peptide hormone that regulates glucose in the blood
2
Q
What is insulin resistance?
A
This is when organs are unresponsive to insulin
3
Q
How is insulin resistance diagnosed?
A
There are often no indicators. If risk factors are present then healthcare professionals may investigate
4
Q
What are the mechanisms of insulin resistance?
A
Impairment of insulin signalling - skeletal muscle insulin resistance
Inflammation - adipose tissue insulin resistance
Pathway-selective hepatic insulin resistance
5
Q
What is the hyperinsulinaemic-Euglycaemic Clamp?
A
This is the gold standard method to measure insulin sensitivity
