Instrumentation Quiz 1

Question 0

Decreased levels of haptoglobin

Answer 0

Hemolytic anemia or Hemolysis from a transfusion

Question 1

Increased levels of alpha-2 macroglobulin

Answer 1

Nephrotic syndrome, protein losing enteropathies, toxemia pregnancy, diabetes, inflammation

Question 2

Increased levels of haptoglobin

Answer 2

Inflammation

Question 3

Where does transferrin migrate to

Answer 3

Beta region

Question 4

Increased beta globulin region

Answer 4

Iron deficiency anemia and lipemia

Question 5

Increase gamma globulin region

Answer 5

Proliferative or inflammation

Question 6

What are the three negative acute phase reactants proteins

Answer 6

Albumin transferrin and transthyretin

Question 7

What is the purpose for performing immunofixation electrophoresis

Answer 7

To identify monoclonal gammopathies in the urine or serum

Question 8

What proteins can be identified by Immunofixation

Answer 8

IgG IgM IgA

Kappa and lambda light chain

Question 9

Acid electrophoresis will separate hemoglobin S from what two hemoglobins

Answer 9

Hemoglobin D or G

Question 10

I said electrophoresis will separate hemoglobin C from what other hemoglobins

Answer 10

Hemoglobin E or D

Question 11

What are three causes of an increase CSF albumin

Answer 11

Influx of serum albumin and bacterial meningitis, Guillain-Barre, trauma

Question 12

What disease can alpha-1 anti-tripsin be used to diagnose

Answer 12

Adult and juvenile cirrhosis

Question 13

What conditions are associated with alpha-1 anti-tripsin efficiency

Answer 13

Neonatal distress syndrome, severe protein losing disorders, and pulmonary emphysema

Question 14

Measurement of antistreptolysin oh is routinely use for the diagnosis and management what two conditions

Answer 14

Acute rheumatic fever and acute glomerulonephritis

Question 15

What is complement

Answer 15

A group of serum proteins that destroy infectious agents

Question 16

Decreases in both complement three and complement four levels are associated with what general condition

Answer 16

Immunological disorders especially those with deficiencies of complement

Question 17

What is Ceruloplasmin

Answer 17

A copper oxidase enzyme that may be important for the regulation of oxidation including that secondary to the Ionic state of iron another metallic ions

Question 18

What are two disorder assessed by measuring ceruloplasm

Answer 18

Wilsons or Menkes kinky hair syndrome

Question 19

List three conditions associated with increased serum albumin levels of monoclonal free light chains

Answer 19

Malignant proliferative cancer like multiple myeloma, primary amyloidosis, light chain deposition disease

Question 20

List of disease associated with increased serum polyclonal light chains

Answer 20

SLE

Question 21

To diseases associated with increased urinary free light chains

Answer 21

Kidney disease or multiple myeloma

Question 22

What are Bence-Jones proteins

Answer 22

Monoclonal urinary free light chains associated with lymphoid malignancy

Question 23

Where is C- reactive proteins synthesized and what are five factors that initiates synthesis

Answer 23

Hepatocytes

Antigens, immune complexes, bacteria, fungi, trama

Question 24

Decrease levels of serum albumin

Answer 24

Protein loss because of kidney or intestine, hepatic disease, anemia, inflammation