Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Daridorexant > Insomnia treatment marketplace > Flashcards

Insomnia treatment marketplace Flashcards

1
Q

How many classes of prescription drugs are there for insomnia?

A

5

1) Benzodiazepines
2) Z- drugs
3) Melatonin receptor agonists
4) Antidepressants
5) DORAs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is a benzodiazepine?

A

A drug which slows down messages traveling between the brain and body. They are also minor tranquilizers usually prescribed by doctors to relieve stress and anxiety and help people sleep.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are some common benzodiazepines?

A

Valium, Xanax, Halcion, Ativan, and Klonopin.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the mechanism of action for benzodiazepines?

A

They bind to the GABA-A receptor…. Thereby increases the affinity for the GABA to the GABA receptor site. This results in a reduction in anxiety and a greater feeling of calm.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is GABA?

A

Gamma-aminobutyric acid…
It is the primary inhibitory neurotransmitter in the brain. It reduces neuron all activity of target cells through its binding to GABA receptors present on the cell surface.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are Z-drugs?

A

Non-benzodiazepines often referred to as Z-drigs. They are a class of psychoactive drugs that are very benzodiazepine-like in nature.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are some of the Z drugs

A

Lunesta (Eszopiclone), Sonata (Zaleplon), Ambien (Zolpidem), and Ambien CR (Zolpidem CR).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What is Z-drug mechanism of action?

A

They work by slowing down brain activity. They work on the central nervous system and directly affect the GABA receptors. GABA receptors produce natural sedative like effevts, so Z drugs in enhance the effects of GABA transmission, like benzodiazepines. This slows down activity in the brain and central nervous system and induces sleep.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What is a melatonin receptor agonist?

A

Analogoues of melatonin that bind to and activate the melatonin receptor. Agonists of the melatonin receptor have a number of therapeutic applications including treatment of sleep disorders and depression. Selectively target specific receptors in the brain that are responsible for controlling the bodies sleep wake cycle. He works by mimicking melatonin, a naturally occurring hormone that is produced during sleep.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are some of the common melatonin receptor agonists?

A

Rozerem (Ramelteon) and Hetlioz (tasimelteon).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is an agonist?

A

A substance that acts like another substance and therefore stimulates an action.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is an anti-depressant?

A

Anti-depressants or medication’s that can help relieve symptoms of depression, social anxiety disorder, anxiety disorders, and seasonal affective disorder. 

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

How do antidepressants work?

A

They work by balancing chemicals in your brain called neurotransmitters that affect mood and emotions. These Depression medicines can help improve your mood, help you sleep better, and increase your appetite in concentration.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is the name of a common antidepressant?

A

Silenor (doxepin)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is a Dora?

A

Duel Orexin receptor antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the Dora mechanism of action?

A

A type of sleep medication that blocks the effects of the neurotransmitter Orexin. Orexin is a neurotransmitter that produces wakefulness. DORAs bind to Orexin receptor-1 and Orecin receptor-2, blocking the effects of Orexin, reducing wakefulness, and helping people to sleep.

17
Q

What are two doors?

A

Belsomra (Suvorexant) and Dayvigo (lemborexant)

18
Q

What does DSM-5 stand for?

A

Diagnostic and statistical manual of mental disorders

19
Q

What is secondary insomnia?

A

When symptoms of insomnia arise from a primary medical illness, mental disorder, or other sleep disorders. It may also arise from the US, miss you, or exposure to certain substances.

20
Q

What is primary insomnia?

A

Difficulty initiating sleep, difficulty maintaining sleep or chronic non-restorative sleep which persists longer than three weeks despite having adequate opportunity for sleep and results in impaired daytime functioning

21
Q

What is the definition of sleep maintenance?

A

Staying asleep for the desired or planned amount of time after initially falling asleep.

22
Q

What is the a AASM?

A

American Academy of sleep medicine

Daridorexant (4 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions