Insomnia-Gentry Flashcards

1
Q

How does DSM5 treat insomnia?

A

used to only be considered a symptom of another disorder

now considered its own disorder

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2
Q

What are the DSM 5 criteria for insomnia disorder?

A

A) A predominant complaint of dissatisfaction with sleep quantity or quality, associated with one (or more) of the following symptoms:

- Difficulty initiating sleep
  - Difficulty maintaining sleep (i.e., frequent awakening with problems returning to sleep)
  - Early morning awakening with the inability to return to sleep

B) The sleep disturbance causes clinically significant distress or impairment in social, occupational or other important areas of functioning.

C&D) Sleep difficulty occurs at least 3 nights per week and present for at least 3 months.

E. Sleep difficulty occurs despite adequate opportunity to sleep.

F. The insomnia is not better explained by and does not occur exclusively during the course of another sleep-wake disorder (i.e. narcolepsy, sleep apnea, parasomnia).

G. Insomnia not attributable to the physiological effects of a substance (i.e. drug abuse, medication).

H. Co-existing mental and medical disorders do not adequately explain the predominant complaint of insomnia.

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3
Q

How prevalent is insomnia?

A

1/3 US adults some sleep problem
50% of primary care patients
12% chronic insomnia

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4
Q

Which gender, age group is insomnia related to?

A

women

older adults

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5
Q

What are some chronic medical & psychiatric problems that are associated with insomnia?

A

Depression, PTSD, substance use
Other sleep disorders (comorbid with sleep apnea)
Chronic pain/medical disorders
The prevalence of sleep disturbances ranges from 50-88%.

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6
Q

How can insomnia be disabling?

A

difficulties with intellectual, social, vocational functioning
less job satisfaction, lower performance scores, less productivity, higher rates of being absent
pain

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7
Q

What are other conditions that people with insomnia are more likely to suffer from?

A
Pain conditions
Gastrointestinal distress
Hypertension
Heart disease
May be risk factor for diabetes
Depression
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8
Q

Describe the overlap of depression & insomnia.

A

Up to 90% of those with MDD complain of sleep problems.
Depression disturbed sleep is associated with:
Increased symptom severity
Slower and lower rates of remission
Higher treatment dropout rates
Less stable response to treatment
Increase suicide risk

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9
Q

T/F Patients with chronic insomnia are between 2 and 6 times more likely to have new-onset or recurrent episodes of depression as compared to patients w/o chronic insomnia.

A

True.

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10
Q

T/F Sometimes when depression is resolved, insomnia remains.

A

True. Then the patient is more susceptible to another bout of depression.

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11
Q

What are some examples of nonbenzodiazepine receptor agonists used for sleep treatment?

A

Zolpidem (Ambien), Zolpidem ER (Ambien CR), Zaleplon (Sonata), Eszopiclone (Lunesta)

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12
Q

What are the pros to nonbenzos?

A

Bind to sub-types of GABA receptors that specifically modulate sleep and therefore are thought to have less unwanted side effects.

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13
Q

What are the cons to nonbenzos?

A

Drowsiness, dizziness, unsteadiness of gait, rebound insomnia and memory impairment have been reported.

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14
Q

What are some benzos used for sleep treatment?

A

Benzodizepines: Alprazolam (Xanax), Lorazepam (Ativan), Clonazepam (Klonopin), Temazepam (Restoril), Diazpepam (Valium).

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15
Q

What are the pros for benzos for sleep?

A

Pros: Enhance sleep, decrease anxiety.

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16
Q

What are the cons for benzos for sleep?

A

Cons: Daytime sedation, unsteadiness of gait (increase fall risk in elderly), higher risk of tolerance, dependence, withdrawal and risk of abuse.

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17
Q

What are the indications for each of the non-benzos for sleep disturbance?

A

Ambien – approved for falling asleep or sleep onset
Ambien CR for both sleep onset and maintenance
Lunesta –sleep onset and sleep maintenance
Sonata –sleep onset only

18
Q

What are some antidepressants used for sleep?

A

Tricyclic antidepressants: Doxepin (Sinequan), Amitriptyline (Elavil).
Second generation antidepressant: Trazadone (Desyrel), Mirtazapine (Remeron).

19
Q

What are some pros for antidepressants for sleep?

A

used for insomnia & depression

20
Q

What are some cons for antidepressants for sleep?

A

still reported side effects

21
Q

What are some other meds for sleep disturbances?

A

Melantonin Receceptor Agonist: Ramelteon (Rozerem)
**Selective agonist at MT1 and MT2 melatonin receptors
Antihistimine: Diphenhydramine (Benadryl), Hydroxine (Vistaril)
Antipsychotics: Quetiapine (Seroquel), Chlorpromazine (Thorazine), Risperidone (Risperdal), Olanzapine (Zyprexa), and Ziprasidone (Geodon)

22
Q

Which sleep medications are FDA approved?

A

Ambien, sonata, Lunesta, Rozerem, Temazepam and low dose doxepin.

23
Q

What are the indication for ambien, sonata, rozerem, ER ambien, and lunesta?

A

ambien: sleep onset insomnia
sonata: sleep onset
rozerem: sleep onset
ER ambien: sleep onset & maintenance
lunesta: sleep onset & maintenance

24
Q

Why is rozerem awesome?

A

targets sleep wake cycle, & not the CNS

can be used long term with no evidence of abuse & dependence

25
Q

What is a good behavioral treatment for sleep disturbances?

A

Cognitive Behavior Therapy for Insomnia (CBTI) is recommended as the first line treatment by National Institute of Health (NIH) and American Academy of Sleep Medicine.
Goals:
Improve sleep quality
Decrease daytime impairment
Decrease insomnia symptoms
Form a positive & clear association between bed & sleeping
Decrease psychological distress related to sleep deprivation

26
Q

T/F Sleep hygiene is synonymous with CBTI.

A

False.

CBTI consists of 4-6 sessions, can be as short as 30 minutes.

27
Q

What are the predisposing factors for chronic insomnia?

A

biologic traits
psychologic traits
social factors

28
Q

What are precipitating factors for insomnia?

A

medical illness
psychiatric illness
stressful life events

29
Q

What are perpetuating factors for insomnia?

A

excessive time in bed

napping conditioning

30
Q

What are the 2 main drives that affect sleep?

A
  1. homeostatic sleep drive (have to start over in building this when you take a nap)
  2. biological clock-circadian rhythm. melatonin at night. arousal during day.
31
Q

T/F A patient who falls asleep at 3 & sleeps until 11 is a patient with insomnia.

A

False. They might have a circadian rhythm disorder.

32
Q

What is involved in stimulus control for sleep therapy?

A

Works through the extinction of a conditioned arousal- repeated experiences of anxiety, frustration and tension when unable to sleep.

don’t associate the bed with frustrated wakefulness

33
Q

What is sleep restriction therapy?

A

First, reduce time in bed (TIB) to the patients current sleep time.

When unwanted wakefulness has decreased and sleep quality improves, begin expanding TIB.

34
Q

Describe the cognitive arousal related to insomnia.

A

Hyper-attention to “threats” to sleep.
**Clock monitoring
Pre-sleep anticipatory anxiety, arousal producing cognitions.
Attributing poor daytime function, negative mood, and “ill-being” to poor sleep
Avoidance behaviors, rigid sleep-related rules.

35
Q

How do you reduce hyperarousal?

A

Relaxation techniques to help quiet the mind.
Creating “buffer time” before sleep.
Cognitive Therapy:
Understand how thoughts can interfere with sleep.
Educate patients on facts and myths about underlying sleep beliefs.

36
Q

What are contraindications for sleep treatment?

A
  • *Active psychotic symptoms
  • *Current alcohol/drug dependence (minimum 30 days sobriety recommended prior to treatment)
  • *Excessive daytime sleepiness where safety risks are present (drives for work, fall risk, etc.)
  • *Bipolar disorder (caution must used). If you make someone too sleepy w/ sleep restriction-could cause a manic episode.
37
Q

What is the effectiveness of CBTI & Zolpidem?

A

CBTI alone is better than Zolpidem alone.
Acute issues: both together best.
Chronic: CBTI alone is best.

38
Q

CBTI can be helpful with patients who suffer insomnia with other serious conditions…like:

A
Chronic pain 
Fibromyalgia 
Elderly medical patients 
Cancer survivors 
PTSD, and other psychiatric conditions
39
Q

What happens to depressed patients when you treat insomnia?

A

it helps depression

sometimes produces depressive remission

40
Q

What is a good alternative to CBTI?

A

Meditation based interventions (MBSR or MBTI) is shown to be a effective treatment option and could provide alternative to CBTI.

Acceptance and Commitment Therapy (ACT).

41
Q

How can you help people with CPAP machines to use it more?

A

CBT
Motivational Enhancement therapy
exposure therapy for claustrophobic reactions
imagery rehearsal therapy