inner ear Flashcards

1
Q

Be able to label the parts of the organ of corti

A

Look on google doc notes

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2
Q

What are the characteristics of IHC

A

stereocilia in U pattern

1 row

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3
Q

What are the characteristics of OHC

A

stereocilia in V or W pattern

3 rows

*they can emit their own sound because they have a feature called motility

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4
Q

What is motility

A

existing or capable of movement (the ability to move spontaneously and actively)

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5
Q

What is the primary role of the mechanical response of the inner ear

A

convert mechanical vibrations at the stapes and of the inner ear fluids into neural (electrical) responses in the auditory nerve

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6
Q

How is the motion of the basilar membrane described

A

as a paradoxical traveling wave

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7
Q

Why is the basilar membrane paradoxical

A

if you stimulate the apical end, the basal end will move first

Basilar membrane is organized so that it is represented by independent oscillators

Even if you damage one place it can still function
Stiffness gradient works across the entire length of the basilar membrane to enable tonotopic organization

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8
Q

What is the evidence that the basilar membrane is not stretched

A

paradoxical traveling waves

if you cut the BM it does not stretch

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9
Q

What are the two types of otoacoustic emissions

A

spontaneous

evoke

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10
Q

What are otoacoustic emissions evidence of

A

evidence that the basilar membrane is nonlinear

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11
Q

In what percent of ears do spontaneous emissions occur

A

50%

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12
Q

What are transient evoked otoacoustic emissions

A

present a short duration sound in the ear canal of a person

sound sets the outer hair cells into oscillation

can record the echo in the ear canal

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13
Q

What are distortion produce otoacoustic emissions

A

present subject with 2 primary tones: f1 and f2

f2/f1 = the biggest cubic distortion product

measure energy at 2f1-f2 to record the emission

if its audible its a combination tone

f2-f1 = simple difference tone

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14
Q

What are cochlear voltages

A

a voltage in the inner ear

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15
Q

What is an alternating current

A

can either be cochlear microphonic (mimics the stimulus) or action potential

in both cases the stimulus is induced

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16
Q

What is direct current

A

can either be resting potentials or summating potentials

summating potentials have stimulus induced and are helpful in diagnosing meneire’s disease

17
Q

What is resting potential and what are the two types

A

voltages that are present in the cochlea in the absence of sound

endocochlear potential: an extracellular potential that you can record in the endolymph

hair cell potential: an intracellular potential

18
Q

What is the total voltage gradient between the EP and the hair cell potential

A

160 mV

19
Q

anything that we hear has to be represented through what?

A

the firing of the 8th auditory nerve

20
Q

What are afferent fibers
(what are the two types)

A

carry information up to the central auditory system

radial fibers: comprise 85-95% of the total number
- innervate only inner hair cells
- 20:1 ICH ratio, many to 1
- primarily responsible for carrying information about sound to the brain

outer spiral fibers: comprise 5-15% of fibers
- innervate only the outer hair cells
- unmyelinated, skinny, slowly conducting
- 1:10 OHC ratio, 1 to many)
unknown function

21
Q

what are efferent fibers

A

carry information back down from the central auditory system

22
Q

What’s on the vertical and horizontal axes of a neural rate intensity function

A

x axis = intensity (dB SPL)

y axis = firing rate (spikes/sec)

23
Q

when no sound is presented, what will the neuron fire at

A

its spontaneous rate

24
Q

What kind of relationship do Spontaneous rate and threshold have

A

inverse