Innate immunity

Question 1

Phagocytosis must be preceded by:

Answer 1

antigen binding to the phagocyte

Question 2

Phagocytes bind antigens using receptors for:

Answer 2

LPS

Question 3

Pathogens engulfed by macrophages

Answer 3

May survive and replicate in the macrophage phagocytic vesicles

Question 4

An inflammatory immune response:

Answer 4

recruits phagocytes to the site of infection

Question 5

Natural killer cells:

Answer 5

are stimulated to kill infected host cells via carbohydrate binding receptors

Question 6

Interferons:

Answer 6

activate NK cells to kill virus-infected cells
get synthesized by virus infected cells in response to infection
inhibit virus replication in infected cells
stimulate the expression of molecules required for Class I MHC presentation of viral proteins

Question 7

Immune system cell adhesion do NOT:

Answer 7

attract leukocytes to an infection site

Question 8

Early induced immune responses are like adaptive immunity in that they:

Answer 8

involve macrophages and complement

Question 9

Selectins:

Answer 9

are present on both leukocytes and vascular endothelial cells

Question 10

Lymphocyte recirculation:

Answer 10

occurs for both naive and effector leukocytes

Question 11

Phagocytes kill bacteria using:

Answer 11

H2O2
Hydrolytic enzymes
Low pH
Lysozome

Question 12

For a circulating neutrophil to reach the site of inflammation, it must bind to blood vessel endothelial cells and then pass between the endothelial cells in a process called:

Answer 12

extravasation

Question 13

Macrophages are attracted to the site of inflammation by:

Answer 13

Bacterial peptides
Chemokines
C5a
IL-8

Question 14

Inflammatory cytokines produced by macrophages activate all the following EXCEPT:

Answer 14

B cells to secrete acute phase proteins