Antibody

Question 1

An antibody Fab contains:

Answer 1

complementarity determining regions
H and L chain variable regions
one antigen binding region
one H-L interchain disulphide bond

Question 2

Myeloma proteins are:

Answer 2

homogenous antibody molecules secreted by plasma cell tumours

Question 3

The regions of the antibody molecule which does contribute MOST to the affinity of the antibody of the antigen are:

Answer 3

CDR

Question 4

Antibody Fc fragments contain:

Answer 4

complement-binding sites

Question 5

The immunoglobulin isotype is determined by the:

Answer 5

H chain constant region

Question 6

Which statement about epitopes are FALSE?

Answer 6

B cells bind only processed antigen epitopes

Question 7

An example of an antigen epitope from an infectious organism would be:

Answer 7

a peptide on the surface of a virus capsid protein

Question 8

Antibody affinity for antigen depends on:

Answer 8

the complementary shape and charge of each antibody V region for its antigen epitope

Question 9

Avidity:

Answer 9

refers to the strenght of interactions between a multivalent antibody and a multivalent antigen

Question 10

Allotypic determinants are:

Answer 10

amino acid differences encoded by different alleles for the same H and L chain

Question 11

IgG is NOT:

Answer 11

the largest
(IgM is)