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The Immune System > Innate Immunity > Flashcards

Innate Immunity Flashcards

1
Q

Most prevalent leukocyte

A

Neutrophil

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2
Q

Granulocytes

A

Neutrophil
eosinophil
basophil

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3
Q

circulating agranulocytes

A

Monocytes

lymphocytes

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4
Q

After entering tissue, monocyte turn into:

A

macrophages

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5
Q

The principal leukocytes that mediate acute inflammation:

A

Neutrophils

monocytes (macrophages)

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6
Q

Immature neutrophils exhibit:

A

chromatin appears as single band instead of 3-5 clumps

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7
Q

highly phagocytic

A

neutrophil

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8
Q

two ways neutrophils kill

A

reactive oxygen species (ROS) - toxin

protease and other enzymes

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9
Q

Neutrophils extrude DNA when they encounter large number os pathogens. This is known as:

A

Neutrophil extracellular traps (NET)

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10
Q

rare, circulate in blood stream, non-phagocytic granulocytes

A

Basophil

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11
Q

Non-phagocytic granulocyte, resides in tissues

A

mast cells

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12
Q

contain histamine

A

mast cells and basophils

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13
Q

Kills larger targets such as paracytes

A

eosinophil

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14
Q

phagocytic granulocyte

A

eosinophil

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15
Q

participates in allergic responses and airway hyperresponsiveness

A

eosinophils

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16
Q

macrophage in the liver

A

kupffer cell

17
Q

the movement of a cell toward or away from a chemical stimulus

A

chemotaxis

18
Q

phagocytes use what to move toward a damaged cell?

A

pseudopods

19
Q

Most critical cell for communication between innate and adaptive immune systems

A

Dendritic cells

20
Q

antibodies or complement proteins from the host coat the microbe surface

A

opsonization

21
Q

Triggers that active innate immunity

A

Danger-associated molecular patterns

  1. tissue damage
  2. Cellular death
  3. cellular stress
22
Q

When tissue damage occurs without pathogen invasion (sprained ankle, etc)

A

sterile inflammation

23
Q

subset of pattern recognition receptors (PRR) that mediate pathogen recognition in the innate immune system.

A

Toll-like receptors

24
Q

Recognize components of bacterial, yeast, or parasite cell membranes

A

Toll-like receptors (TCR)

The Immune System (3 decks)

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