Functional Anatomy

Question 1

Primary lymphoid organs

Answer 1

Thymus and Bone Marrow

Question 2

T-cells develop in the:

Answer 2

Thymus

Question 3

B-cells develop in the:

Answer 3

Bone Marrow

Question 4

Secondary lymphoid organs

Answer 4

lymph node, lymphatic vessels, spleen

Question 5

Hematopoiesis occurs in the:

Answer 5

Bone Marrow

Question 6

Three blood lineages developed from HSC

Answer 6

Erythroid (erythrocytes- RBC)
megakaryocytes (platelet producing)
myeloid and lymphoid (develop into WBC)

Question 7

Somatic gene rearrangement

Answer 7

Increases possibility of generating different unique antigen-binding sites on the receptor.

Question 8

positive selection

Answer 8

T-cell receptor (TCR) tested in thymus to ensure they are functional

Question 9

negative selection

Answer 9

TCR tested for reactivity and deleted if they are activated by self antigen.

Question 10

Negative selection prevents:

Answer 10

release of lymphocytes that could trigger autoimmune response

Question 11

what happens when there is damage to lymphatic flow

Answer 11

Edema

Question 12

cells and fluid enter lymph node through:

Answer 12

afferent lymphatic vessels

Question 13

cells leave the lymph node via:

Answer 13

efferent lymphatic vessel

Question 14

unique feature of spleen

Answer 14

Marginal zone

Question 15

Significant function of marginal zone b cells

Answer 15

protection from HIV and other infections (viral and bacterial).

Question 16

Largest lymphoid organ in the human body

Answer 16

GALT - gut-associated lymphoid tissue