Innate immune response Flashcards
interferons
a group of cytokines released by infected cells that act as warning signals to nearby cells so they can prepare `
dendritic cells
carry fragements of pathogens to the lymph nodes to present them to cells of the specific immune response
degranulation
the release of anti-microbial and toxic materials from the natural killer cells
steps of phagocytosis
recognition of pathogens, engulfment of pathogen into a phagosome, digestion/destruction of pathogen, undigested ‘leftovers’ exocytosed`
neutrophils
remove microbes by phagocytosis
macrophages
remove pathogens, dead cells, and cell debris
eosinophils
assist in defending against larger parasitic agents that are too large to be engulfed by phagocytosis. Attack using toxic chemicals released from cystoplasmic granules`
natural killer cells
klls virus infected cells through apoptosis killing the cell and the virus it contains. This prevents the spread of the virus to any cells
complement proteins
proteins that lyse the cell wall of an antigen
Inflammatory response
a short term response, area becomes hot, red, and swollen. Mast cells alert the immune system that something is wrong and release histamines which causes vasodilation
cellular stage
neutrophils leave the bloodstream and attract macrophages as they go, phagocytosis of pathogens occurs, leading to an abscess forming made of dead phagocytes and skin cells
vasodilation
the dilation of blood cells