Inj. Anesthesia Flashcards
Best for brain surgery
Thiopental
Thiopental- MOA
GABAr and thiopental-r
Thiopental- TI
LOW- danger
Thiopental- CRI?
No, long context sensitive
Thiopental- wake due to
Redistribution
Thiopental- contras
Liver dz, PSS
Best for liver
Propofol
Propofol- MOA
GABAr
Propofol- context half life
Short! fast clearance
Propofol- TI
LOW- danger
Propofol- wake
Bolus- redistribution, CRI- elimination
Propofol- SE
Methemoglobinemia, D and malaise in cats, resp depression
Propofol- Contras
Respiratory compromised
Best for heart
Etomidate
Etomidate- SE
Endocrine- supression of adrenal –> steroids –> glucose for energy
Etomidate- TI
HIGH- safe
Ketamine- contras
Low protein! due to high protein binding
Ketamine- TI
HIGH! safe
Only non-GABA
Ketamine
Ketamine- MOA
NMDA antagonist prevent glutamate binding; opioid, muscarinic
Which drug provides analgesia?
Ketamine only