inheritance and Pedrigree trees

Question 1

describe the pedigree diagram of autosomal recessive

Answer 1

males and females are equally affected
disease can come from out of no where
diseases can skip generations
both parents of affected individuals are heterozygous

Question 2

Give an example of autosomal dominant

Answer 2

Huntingtons disease

Question 3

Describe the pedigree diagram of autosomal dominant

Answer 3

both males and females are affected
every affected individual will have one affected parent
disease cannot skip a generation

Question 4

give an example of autosomal recessive

Answer 4

cystic fibrosis

Question 5

Give an example of x linked recessive

Answer 5

Haemophilia A

affects hemizygous males and homozygous females

more common in males
heterozygous female carrier has 50% chance of having affected sons
affected males cannot give trait to sons

Question 6

describe a pedigree tree of x linked recessive

Answer 6

males and females unequally affected
every affected male will have a heterozygous carrier mother
every affected female will have affected father and carrier mother
daughters of affected males heterozygous

Question 7

Give and example of codominance

Answer 7

allele for glycoproteins on surface fo red blood cells
either allele for A or B are dominant over each other

or sickle cell anaemia

Question 8

what is complementation and Give an example of complementation

Answer 8

more than one gene can be involved in producing the phenotype

albinism

Question 9

what is linkage

Answer 9

genes on the same chromosome are linked

linked genes do not show independent assortment at meiosis

Question 10

what is recombination frequency?

Answer 10

recombindation frequence between two linked genes is dependent on the distance between genes

how often crossing over occurs - genes that are very close togehter are tightly linked
genes far apart on the same chromosome almost behave as unlinked genes